Molecular evidence for the localization of Plasmodium falciparum immature gametocytes in bone marrow
Blood; 123 (7), 2014
Plasmodium falciparum immature gametocytes are not observed in peripheral blood. However, gametocyte stages in organs such as bone marrow have never been assessed by molecular techniques, which are more sensitive than optical microscopy. We quantified P falciparum sexual stages in bone marrow (n = 174) a...
Anemia/parasitology, Anemia/genetics, Bone Marrow/pathology, Bone Marrow/parasitology, DNA, Protozoan/analysis, Life Cycle Stages/genetics, Malaria, Falciparum/diagnosis, Malaria, Falciparum/genetics, Malaria, Falciparum/parasitology, Molecular Diagnostic Techniques, Plasmodium falciparum/genetics, Plasmodium falciparum/growth & development, Plasmodium falciparum/isolation & purification, Polymerase Chain Reaction, Mozambique