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Duration of vaccine efficacy against malaria: 5th year of follow-up in children vaccinated with rts, s/as02 in mozambique

Campo, Joseph J; Sacarlal, Jahit B C; Aponte, John J; Aide, Pedro; Nhabomba, Augusto J; Dobano, Carlota; Alonso, Pedro L.
Vaccine; 32 (19), 2014
A primary concern for the RTS,S malaria vaccine candidate is duration of protection. The ongoing Phase III trial reported evidence of waning efficacy within the first year following vaccination. Multiple Phase IIb trials demonstrated early waning of efficacy. The longest duration of protection for RTS,S ...
Immunoglobulin G/blood, Antibodies, Protozoan/blood, Malaria Vaccines/immunology, Malaria Vaccines/therapeutic use, Mozambique, Malaria, Falciparum/prevention & control, Parasitemia/prevention & control, Randomized Controlled Trials as Topic, Plasmodium falciparum
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Community response to intermittent preventive treatment delivered to infants (IPTi) through the EPI system in Manhiça, Mozambique

Pool, robert; Munguambe, khatia; Macete, eusebio; Aide, pedro; Juma, geraldina; Alonso, pedro L; Menendez, clara.
Trop. med. int. health; 11 (11), 2006
Objective: To describe attitudes to the expanded programme on immunization (EPI) and intermittent preventive treatment in infants (IPTi), and perceptions of the relationship between them. In particular, whether the introduction of IPTi negatively affects community attitudes to, or use of, EPI; or, conver...
Health Knowledge, Attitudes, Practice, Caregivers/psychology, Delivery of Health Care/methods, Delivery of Health Care/organization & administration, Hematologic Tests/psychology, Immunization/psychology, Malaria Vaccines/therapeutic use, Immunization Programs/organization & administration, Malaria, Falciparum/psychology, Patient Acceptance of Health Care/psychology, Mozambique/epidemiology
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