Methods: We conducted antibiotic susceptibility testing on 157 stool isolates recovered from 129 patients aged between 0 and 80 years with diarrhea, including HIV infected (n = 68) and-uninfected individuals (n = 61), assisted at two health centers in Maputo city. The isolates comprised of 99 Salmonella,...
Agar,
Anti-Bacterial Agents/pharmacology,
Anti-Bacterial Agents/therapeutic use,
Azithromycin,
Bacteria,
Campylobacter,
Diarrhea/microbiology,
Diarrhea/epidemiology,
Drug Resistance, Bacterial,
Drug Resistance, Multiple,
Erythromycin,
Gentamicins/pharmacology,
Gentamicins/therapeutic use,
HIV Infections/complications,
HIV Infections/epidemiology,
Microbial Sensitivity Tests,
Mozambique/epidemiology,
Salmonella,
Sheep,
Shigella,
Tetracycline
Kenga, Darlenne B;
Gebretsadik, Tebeb;
Simbine, Samuel;
Simbine, Samuel;
Maússe, Fabião E;
Charles, Pedro;
Zaqueu, Ernesto;
Fernando, Hermenegilda F;
Sacarlal, Jahit;
Moon, Troy D.
Background: Bacteremia is a major cause of morbidity and mortality worldwide. Children infected with HIV present with patterns of bacteremia generally associated with poor prognosis. In Mozambique, data on bacteremia are sparce.
Methods: We conducted an observational study of HIV-infected and HIV-expose...
Anti-Bacterial Agents/therapeutic use,
Bacteremia/epidemiology,
Bacteremia/drug therapy,
Community-Acquired Infections/drug therapy,
Community-Acquired Infections/epidemiology,
Fever/drug therapy,
HIV Infections/epidemiology,
HIV Infections/complications,
HIV Infections/drug therapy,
Microbial Sensitivity Tests,
Staphylococcal Infections/drug therapy,
Mozambique/epidemiology
Sigauque, Betuel;
Kobayashi, Miwako;
Vubil, Delfino;
Nhacolo, Ariel;
Chauque, Alberto;
Moiane, Benild;
Massora, Sérgio;
Mandomando, Inácio;
Nhampossa, Tacilta;
Bassat, Quique;
Pimenta, Fabiana;
Menendez, Clara;
Carvalho, Maria da Gloria;
Macete, Eusebio;
Schrag, Stephanie J.
Maternal group B streptococcal (GBS) vaccines under development hold promise to prevent GBS disease in young infants. Sub-Saharan Africa has the highest estimated disease burden, although data on incidence and circulating strains are limited. We described invasive bacterial disease (IBD) trends among inf...
Streptococcal Infections/epidemiology,
Mozambique/epidemiology,
Virulence/genetics,
Penicillin Resistance,
Bacterial Infections/epidemiology,
Genome, Bacterial,
Immunity, Maternally-Acquired,
Incidence,
Infant, Newborn,
Microbial Sensitivity Tests,
Multiplex Polymerase Chain Reaction,
Penicillin Resistance/genetics,
Penicillin-Binding Proteins/genetics,
Point Mutation,
Streptococcal Infections/microbiology,
Streptococcal Infections/prevention & control,
Streptococcal Vaccines/pharmacology,
Streptococcus agalactiae/drug effects
Background: Genotypic molecular testing may be very helpful for tuberculosis (TB) drug-resistance surveillance and for treatment guidance in low resource settings.
Methods: Descriptive analysis of M. tuberculosis isolates from Beira Central Hospital, Mozambique, during 2014-2015. Genotype MTBDRplus and ...
Antitubercular Agents/therapeutic use,
Antitubercular Agents/pharmacology,
Drug Resistance, Bacterial/drug effects,
Ethambutol/therapeutic use,
Fluoroquinolones/therapeutic use,
Microbial Sensitivity Tests,
Tuberculosis, Pulmonary/microbiology,
Mycobacterium tuberculosis/isolation & purification,
Mozambique
Background: S. pneumoniae is the leading cause of acute bacterial meningitis (ABM) in children. Vaccination using the 10-valent conjugate vaccine (PCV-10) was recently introduced into the National Immunization Program in Mozambique, but data on serotype coverage of this vaccine formulation are scarce. In...
Anti-Bacterial Agents/pharmacology,
Pneumococcal Vaccines,
DNA, Bacterial/analysis,
Ceftriaxone/pharmacology,
Microbial Sensitivity Tests,
Drug Resistance, Multiple, Bacterial,
Epidemiological Monitoring,
Meningitis, Bacterial/epidemiology,
Meningitis, Bacterial/microbiology,
Meningitis, Bacterial/prevention & control,
Penicillins/pharmacology,
Pneumococcal Infections/immunology,
Pneumococcal Infections/microbiology,
Pneumococcal Vaccines/administration & dosage,
Streptococcus pneumoniae/classification,
Streptococcus pneumoniae/genetics,
Streptococcus pneumoniae/isolation & purification,
Streptococcus pneumoniae/radiation effects,
Polymerase Chain Reaction,
Mozambique/epidemiology
A tuberculose (TB) é uma doença infecciosa que ameaça a humanidade há séculos. Recentemente grandes
avanços foram conseguidos no combate à tuberculose, entretanto a resistência bacilar e a coinfecção pelo
Vírus de Imunodeficiência Humana (HIV) persistem como os principais desafios dos program...
Drug Resistance, Bacterial,
Mycobacterium tuberculosis/drug effects,
Genotype,
Antibiotics, Antitubercular/pharmacology,
Coinfection,
Tuberculosis, Multidrug-Resistant/microbiology,
Prevalence,
Tuberculosis/microbiology,
Microbial Sensitivity Tests,
Mycobacterium tuberculosis/genetics,
HIV Infections/epidemiology,
Mozambique/epidemiology
Nhantumbo, aquino albino;
Cantarelli, vlademir vicente;
Caireão, juliana;
Munguambe, alcides moniz;
Comé, charlotte elizabeth;
Pinto, gabriela do carmo;
Zimba, tomás francisco;
Mandomando, inácio;
Semá, cynthia baltazar;
Gudo, eduardo samo;
Moraes, milton ozório.
Background: In Sub-Saharan Africa, including Mozambique, acute bacterial meningitis (ABM) represents a main cause of childhood mortality. The burden of ABM is seriously underestimated because of the poor performance of culture sampling, the primary method of ABM surveillance in the region. Low quality ce...
DNA, Bacterial/cerebrospinal fluid,
DNA, Bacterial/genetics,
Drug Resistance, Bacterial,
Haemophilus influenzae/drug effects,
Haemophilus influenzae/genetics,
Haemophilus influenzae/isolation & purification,
Meningitis, Bacterial/diagnosis,
Meningitis, Bacterial/epidemiology,
Meningitis, Bacterial/microbiology,
Microbial Sensitivity Tests,
Multivariate Analysis,
Neisseria meningitidis/drug effects,
Neisseria meningitidis/genetics,
Neisseria meningitidis/isolation & purification,
Real-Time Polymerase Chain Reaction/methods,
Reproducibility of Results,
Seasons,
Sensitivity and Specificity,
Severity of Illness Index,
Streptococcus agalactiae/drug effects,
Streptococcus agalactiae/genetics,
Streptococcus agalactiae/isolation & purification,
Streptococcus pneumoniae/drug effects,
Streptococcus pneumoniae/genetics,
Streptococcus pneumoniae/isolation & purification,
Mozambique/epidemiology
Objetivo: El objetivo principal del presente trabajo es el estudio del porcentaje de casos de infección por Chamydia trachomatis (C. trachomatis), Neisseria gonorrhoeae (N. gonorrhoeae), Mycoplasma hominis (Mycoplasma hominis) y Ureaplasma urealyticum (U. urealyticum) y la determinación de la resistenc...
Stress, Psychological,
Drug Collateral Sensitivity,
Aminoglycosides,
Infections,
Mycoplasma hominis,
Microbial Sensitivity Tests,
Drug Resistance, Microbial,
Chlamydia trachomatis,
Sexually Transmitted Diseases,
Coinfection,
Residence Characteristics,
Gender Identity,
Women
Van der Meeren, Birgitta Theodora;
Chhaganlal, Kajal D;
Pfeiffer, Annett;
Gomez, Ermelinda;
Ferro, Josefo J;
Hilbink, Mirrian;
Steidel, Konrad;
Macome, Cesar;
Vondervoort, Francien J;
Wever, Peter C.
Objectives: A prospective surveillance study was conducted to investigate the epidemiology and patterns of antibiotic resistance among uropathogens from hospitalised children in Beira, Mozambique. Additionally, information regarding determinants of a urinary tract infection (UTI) was obtained.
Methods: ...
Anti-Infective Agents/therapeutic use,
Child, Hospitalized,
Drug Resistance, Microbial,
Microbial Sensitivity Tests,
Urinalysis,
Urinary Tract Infections/epidemiology,
Urinary Tract Infections/drug therapy,
Urinary Tract Infections/microbiology,
Mozambique/epidemiology
Mandomand, inacio;
Espasa, mateu;
Valles, xavier;
Pons, maria J;
Jaintilal, dinis;
Mensa, laura;
Macete, eusebio;
Sacarlal, jahit;
Sanz, Sergi;
Sigauque, Betuel;
Abacassamo, fatima;
Alonso, pedro L;
Ruiz, joaquim.
The antimicrobial susceptibility and mechanisms of resistance of 109 Shigella and 40 Salmonella isolates from children with diarrhea in southern Mozambique were assessed. The susceptibility to seven antimicrobial agents was tested by disk diffusion, and mechanisms of resistance were searched by PCR or co...
