Previous studies suggest that neurocysticercosis (NCC), the most common cause of acute symptomatic seizures (ASS), epilepsy and other neuropsychiatric disorders, typically presents with a solitary lesion and focal seizures in children from places where cysticercosis is endemic. We report a series of 3 pa...
Neurocysticercosis/diagnosis,
Antibodies/immunology,
Central Nervous System/drug effects,
Cysticercosis/complications,
Epilepsy/diagnosis,
Headache/complications,
Parasites,
Mozambique/epidemiology,
Biomarkers/metabolism,
Epilepsy/complications,
Epilepsy/drug therapy,
Enzyme-Linked Immunosorbent Assay/methods
Nhama, abel;
Nhamússua, lídia;
Macete, eusébio;
Bassat, quique;
Salvador, crizolgo;
Enosse, sónia;
Candrinho, baltazar;
Carvalho, eva;
Nhacolo, arsénio;
Chidimatembue, arlindo;
Saifodine, abuchahama;
Zulliger, rose;
Lucchi, naomi;
Svigel, samaly s;
Moriarty, leah f;
Halsey, eric s;
Mayor, alfredo;
Aide, pedro.
Background: Artemisinin-based combination therapy (ACT) has been the recommended first-line treatment for uncomplicated malaria in Mozambique since 2006, with artemether–lumefantrine (AL) and amodiaquine–artesunate (AS–AQ) as the first choice. To assess efficacy of currently used ACT, an in vivo...
Mozambique/epidemiology,
Artemether/administration & dosage,
Artesunate/administration & dosage,
Algorithms,
Malaria, Falciparum,
Malaria/drug therapy,
Lumefantrine,
Infections,
Efficacy/methods,
34628,
Patients,
Parasites,
Lost to Follow-Up,
Polymerase Chain Reaction,
Recurrence,
Safety,
Therapeutics,
Molecular Diagnostic Techniques
Fonseca, ana maria;
Raquel, gonzález;
Bardaji, açucene;
Rupérez, maria;
Llorenç, quintó;
Pau, cisteró;
Gupta, himanshu;
Hegewisch, taylor;
Brew, joe;
Dobanõ, carlota;
Aponte, Joao j;
Menendez, Clara;
Mayor, alfredo;
Jairoce, chenjerai;
Nhacalo, arśenio;
Sevene, esperança;
Machete, eusébio;
Vala, Anifa;
Savour, charfudin;
Adam, nicaise tuikue;
Massougbodji, achille;
Koriuuki, simon;
Puma, pedro;
Lopez, marta.
Pregnant women constitute a promising sentinel group for continuous monitoring of malaria transmission. To identify antibody signatures of recent Plasmodium falciparum exposure during pregnancy, we dissected IgG responses against VAR2CSA, the parasite antigen that mediates placental sequestration. We use...
A schistosomose e as helmintoses intestinais são endémicas em Moçambique, afetando sobretudo crianças e jovens dos meios suburbanos e rurais. O presente estudo foi realizado nos distritos de Quelimane e Gurué, na província de Zambézia-Moçambique, envolvendo 357 crianças escolares entre os cinco ...
Parasites/parasitology,
Mollusca/metabolism,
Mozambique/epidemiology,
Parasitic Diseases/diagnosis,
d0160210,
d0072390,
Schistosomiasis/virology,
Parasitic Diseases/epidemiology,
Feces/parasitology,
Urine/microbiology,
Schistosoma haematobium/drug effects,
Weights and Measures/instrumentation
Human immunodeficiency virus (HIV)-1 infection has an important impact on malaria. Plasmodium falciparum
and HIV-1 co-infected patients (Pf/HIV) present with a high degree of anaemia, enhanced parasitaemia and decreased
CD4+ T cell counts, which increase the risk of developing severe malaria. In addition...
Background: Protection against clinical malaria episodes is acquired slowly after frequent exposure to malaria parasites. This is reflected by a decrease with increasing age in both parasite density and incidence of clinical episodes. In many settings of stable malaria transmission, the presence...
Malaria/epidemiology,
Temperature,
Sensitivity and Specificity,
Blood/diagnostic imaging,
Precautionary Principle,
Prevalence,
Plasmodium falciparum,
Parasites/genetics,
Microscopy,
Logistic Models,
Malaria/blood,
Confidence Intervals,
Surveys and Questionnaires/statistics & numerical data,
Infections,
Age Groups,
Fever/diagnosis,
Cost of Illness,
32511/methods,
Fingers/growth & development,
Mozambique
Enosse, Sonia;
Dobaño, Carlota;
Quelhas, Diana;
Aponte, John J;
Lievens, Marc;
Leach, Amanda;
Sacarlal, Jahit;
Greenwood, Brian;
Milman, Jessica;
Dubovsky, Filip;
Cohen, Joe;
Thompson, Ricardo;
Ballou, W Ripley;
Alonso, Pedro L;
Conway, David J;
Sutherland, Colin J.
The candidate malaria vaccine RTS,S/AS02A is a recombinant protein containing part of the circumsporozoite protein (CSP) sequence of Plasmodium falciparum, linked to the hepatitis B surface antigen and formulated in the proprietary adjuvant system AS02A. In a recent trial conducted in children younger th...
Malaria,
T-Lymphocytes/immunology,
Parasites/parasitology,
Cells,
Malaria, Falciparum/diagnosis,
Malaria Vaccines/immunology,
Protozoan Infections/transmission,
Malaria, Falciparum/transmission,
Malaria, Falciparum/prevention & control,
Mozambique
Malaria is one of the most important diseases among children in tropical Africa.
Although the highest morbidity rate is observed in young children, older children attending primary still have level of parasite rats.
It seems malaria may have some effects on school outcome measures, Such as increasing day...
Malaria,
Parasites,
Chloroquine,
Plasmodium,
Blood,
Burns,
Trypanosomiasis,
Immunodiffusion,
Diagnosis,
Death,
Health,
Midwifery,
Health Surveys
