Martinez, Francisco Jose;
Massinga, Arsenia J;
Jesus, Áuria;
Ernesto, Rita M;
Jiménez, Pablo Cano;
Oms, Álvaro Chiner;
Navarro , Inmaculada Gómez;
Fernández, Marina Guillot;
Guinovart, Caterina;
Sitoe, António;
Vubil, Delfino;
Bila, Rubão;
Gujamo, Rufino;
Enosse, Sónia;
Serrano, Santiago Jiménez;
Puente, Manuela Torres;
Comas, Iñaki;
Mandomando, Inácio;
G López, Mariana;
Mayor, Alfredo.
From the start of the SARS-CoV-2 outbreak, global sequencing efforts have generated an unprecedented amount of genomic data. Nonetheless, unequal sampling between high-income and low-income countries hinders the implementation of genomic surveillance systems at the global and local level. Filling the kno...
Bero, Diocreciano Matias;
da Silva, Edson Elias;
Junior Ivanildo, Pedro de Sousa;
Nhassengo, Sheila António;
Machado, Raiana Scerni;
Bauhofer, Adilson Fernando Loforte;
Chilaúle, Jorfélia José;
Munlela, Benilde;
Guimarães, Esperança;
Moiane, Idalécia Cossa;
Sambo, Júlia;
Elda, Anapakala;
Cassocera, Marta;
Coutinho-Manhique, Lena;
Chissaque, Assucênio;
Langa, Jerônimo J;
Burlandy, Fernanda;
Deus, de Nilza.
Enteroviruses (EV) are predominantly enteric viruses, present in all parts of the world causing disease in humans with a broad spectrum of clinical presentations. The purpose of this study was to identify non-polio enteroviruses (NPEV) in stool samples collected from children with acute gastroenteritis (...
Munlela, Benilde;
João, eva d;
Donato, celeste m;
Strydom, amy;
Boene, simone s;
Chissaque , assucênio;
Bauhofer, adilson f. l;
Langa, jerónimo;
Cassocera, Marta;
Cossa-Moiane, Idalécia;
Chilaúle, jorfélia j;
O’Neill, hester g;
de Deus, nilsa.
Mozambique introduced the rotarix® vaccine (gsk biologicals, rixensart, belgium) into the na-tional immunization program in september 2015. Although g1p[8] was one of the most prevalent genotypes between 2012 and 2017 in mozambique, no complete genomes had been sequenced to date. here we report whole ge...
Jofrin, léa;
Goodman, steven m;
Wilkinson, david a;
Ramasindrazana, beza;
Lagadec, erwan;
Minter, gildas le;
Santos, andréa dos;
Schoeman, m corrie;
Sookhareea, rajendraprasad;
Tortosa, Pablo;
Gudo, eduardo s;
Mavingui, Patrick;
Lebarbenchon, camille.
Bats provide key ecosystem services such as crop pest regulation, pollination, seed dispersal, and soil fertilization. Bats are also major hosts for biological agents responsible for zoonoses, such as coronaviruses (CoVs). The islands of the Western Indian Ocean are identified as a major biodiversity hot...
Mozambique,
Prevalence,
Indian Ocean Islands/epidemiology,
Social Control, Formal,
Coronavirus Infections/epidemiology,
Coronavirus Infections/veterinary,
Coronavirus Infections/virology,
DNA, Viral/genetics,
Ecosystem,
Evolution, Molecular,
Genetic Variation,
Host Specificity,
Phylogeny,
Mass Screening,
Phylogeography/methods,
RNA-Dependent RNA Polymerase,
Alphacoronavirus/genetics,
Betacoronavirus/genetics,
Chiroptera/virology,
RNA-Dependent RNA Polymerase/genetics,
Real-Time Polymerase Chain Reaction,
Zoonoses/epidemiology,
Zoonoses/virology
Joao, eva dora;
Stroydon, amey;
Oneil g, hester;
Cumba, assa;
Cossecera, marta;
Acacio, sozinho;
Mandomando, inácio;
Motanyane, lithabiso;
Page, nicola;
Deus, nilsa de.
In Mozambique rotavirus (RV) was shown to be the greatest cause of acute diarrhoea in infants from 0 to 11 months, and in 2015, national rotavirus vaccination was introduced. As with other developing countries, there is very limited active strain characterisation. Rotavirus positive clinical specimens, c...
Gastroenteritis/virology,
Genotype,
Rotavirus Infections/virology,
Acute Disease,
Phylogeny,
Rotavirus/genetics,
Antigens, Viral/genetics,
Genetic Variation,
Gene Expression Regulation, Viral,
Mozambique,
Epitopes/genetics
Hoarau, flora;
Joffrin, léa;
Schoeman, m. corrie;
Lagadec, erwan;
Ramasindrazana, beza;
Santos, andréa dos;
Goodman, steven m;
Gudo, eduardo s;
mavingui, patrick;
Lebarbenchon, camille.
Astroviruses (AstVs) are responsible for infection of a large diversity of mammalian and avian species, including bats,
aquatic birds, livestock and humans. We investigated AstVs circulation in bats in Mozambique and Mayotte, a small
island in the Comoros Archipelago located between east Africa and Madag...
Enfuvirtide was the first fusion inhibitor approved by the Food and Drug Administration (FDA) in 2003 for HIV-1 infection in treatment-experienced patient. It is the first approved antiviral agent to attack the HIV life cycle in its early stages. For HIV fusion to occur, the HR1 and HR2 domains in the gp...
HIV-1/genetics,
Amino Acid Sequence,
Anti-HIV Agents,
Cluster Analysis,
Drug Resistance, Viral,
Enfuvirtide,
Genotype,
HIV Envelope Protein gp41/genetics,
HIV Infections/virology,
HIV-1/classification,
Molecular Sequence Data,
Mozambique,
Mutation, Missense,
Peptide Fragments,
Phylogeny,
Polymorphism, Genetic,
RNA, Viral,
Sequence Alignment,
Sequence Analysis, DNA,
Treatment Failure
Bila, Dulce Celina Adolfo;
Young, Pedro;
Merks, Harriet;
Vubil, Adolfo Salvador;
Mahomed, Mussagy;
Augusto, Angelo;
Abreu, Celina Monteiro;
Mabunda, Nédio Jonas;
Brooks, James, I;
Tanuri, Amilcar;
Jani, Ilesh Vinodrai.
Objective: InMozambique, highly active antiretroviral treatment (HAART) was introduced in 2004 followed by decentralizationandexpansion, resulting inamorethan20-fold increase incoverageby2009. ImplementationofHIV drugresistancethresholdsurveys (HIVDR-TS) iscrucial inorder tomonitor theemergenceof transmi...
Anti-HIV Agents/pharmacology,
Anti-HIV Agents/therapeutic use,
Antiretroviral Therapy, Highly Active,
Mozambique,
Drug Resistance, Viral/genetics,
HIV Infections/therapy,
HIV Infections/epidemiology,
HIV Infections/virology,
HIV-1/classification,
HIV-1/radiation effects,
HIV-1/genetics,
Mozambique/epidemiology,
Mutation,
Phylogeny
Multiple-locus variable-number tandem repeat analysis (MLVA) is useful to establish transmission routes and sources of infections for various microorganisms including Mycobacterium tuberculosis complex (MTC). The recently released SITVITWEB database contains 12-loci Mycobacterial Interspersed Repetitive ...
Bacterial Typing Techniques,
Bayes Theorem,
Genetic Loci/genetics,
Genotype,
Internationality,
Interspersed Repetitive Sequences/genetics,
Microsatellite Repeats/genetics,
Mycobacterium tuberculosis/classification,
Mycobacterium tuberculosis/genetics,
Phylogeny,
Phylogeography
Aide, Pedro;
Dobano, Carlota;
Sacarlal, Jahit;
Aponte, John J;
Mandomando, Inácio;
Guinovart, Caterina;
Bassat, Quique;
Renom, Montse;
Puyol, Laura;
Macete, Eusebio;
Herreros, Esperanza;
Leach, Amanda;
Dubois, Marie-Claude;
Demoitie, Marie-Ange;
Lirvrens, Marc;
Vekemans, Johan;
Loucq, Christian L;
Ballou, W. Ripley;
Cohen, Joe;
Alonso, Pedro L.
Previous studies with the malaria vaccine RTS,S/AS02A in young children in a malaria endemic area of Mozambique have shown it to have a promising safety profile and to reduce the risk of Plasmodium falciparum infection and disease. In this study, we assessed the antibody responses to the P. falciparum an...
