Safety and efficacy of dihydroartemisinin-piperaquine for intermittent preventive treatment of malaria in pregnant women with HIV from Gabon and Mozambique: a randomised, double-blind, placebo-controlled trial
Lancet, Infect. dis.; 24 (5), 2024
For this randomised, double-blind, placebo-controlled clinical trial, women with HIV attending the first antenatal care clinic visit, resident in the study area, and with a gestational age up to 28 weeks were enrolled at five sites in Gabon and Mozambique. Participants were randomly assigned (1:1) to rec...
Antimalarials/administration & dosage, Artemisinins/administration & dosage, Double-Blind Method, Drug Combinations, Gabon, HIV Infections/complications, Malaria/therapy, Malaria/prevention & control, Piperazines, Pregnancy Complications, Quinolines/administration & dosage, Treatment Outcome, Trimethoprim, Sulfamethoxazole Drug Combination, Antimalarials/therapeutic use, Antimalarials/adverse effects, Artemisinins/adverse effects, Artemisinins/therapeutic use, Mozambique/epidemiology, Pregnancy Complications, Infectious/therapy, Pregnancy Complications, Infectious/prevention & control