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Effect of 10-Valent Pneumococcal conjugate vaccine on streptococcus pneumoniae nasopharyngeal carriage among children less than 5 years old: 3 years post-10-valent Pneumococcal conjugate vaccine introduction in Mozambique

Valenciano, Sandra J; Moiane, Benild; Lessa, Fernanda C; Chaúque, Alberto; Massora, Sergio; Pimenta, Fabiana C; Mucavele, Helio; Verani, Jennifer R; Carvalho, Maria da Gloria; Whitney, Cynthia G; Tembe, Nelson; Sigaúque, Betuel.
Journal of the Pediatric Infectious Diseases Society; 10 (8), 2021
Pneumococcal pneumonia is the leading infectious cause of childhood mortality with an estimated 257 000 deaths globally among children aged 1–59 months in 2015 [1, 2]. Streptococcus pneumoniae is the most common cause of bacterial pneumonia in children [3]. HIV-infected children are at increased risk ...
Pneumococcal Infections/epidemiology, Pneumococcal Infections/prevention & control, Streptococcus pneumoniae, Pneumococcal Vaccines, Serogroup, Mozambique/epidemiology, Carrier State/epidemiology
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Early Declines in Vaccine Type Pneumococcal Carriage in Children Less Than 5 Years Old After Introduction of 10-valent Pneumococcal Conjugate Vaccine in Mozambique

Sigauque, betuel; Moiane, benild; Massora, sergio; Pimenta, fabiana; Verani, jennifer r; Mucavele, helio; Chauque, alberto; Santos, rita t; Carvalho, maria da gloria; Whitney, cynthia g; Leesa, fernanda c.
Journal of the Pediatric Infectious Diseases Society; 37 (10o), 2018
Pneumococcal carriage is a precursor of invasive pneumococcal disease. Mozambique introduced 10-valent pneumococcal conjugate vaccine (PCV10) in April 2013, using a 3-dose schedule without a booster. We evaluated PCV10 impact on pneumococcal carriage and colonization density by HIV status. Methods: We c...
Mozambique/epidemiology, Pneumococcal Infections/epidemiology, Carrier State/epidemiology, HIV Infections/complications, Vaccination, Child, Pneumonia
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Serotype distribution and antibiotic susceptibility of invasive and nasopharyngeal isolates of Streptococcus pneumoniae among children in rural Mozambique

Valles, Xavier; Flannery, Brendan; Roca, Anna; Mandomando, Inacio; Sigauque, Betuel; Sanz, Sergi; Schuchat, Anne; Levine, Myron; Soriano-Gabarro, Montserrat; Alonso, Pedro.
Trop. med. int. health; 11 (3), 2006
Objective: To describe and compare serotype distribution and antibiotic susceptibility of invasive and nasopharyngeal isolates of Streptococcus pneumoniae from children in rural Mozambique. Methods: From August 2002 to July 2003, we prospectively obtained invasive pneumococcal isolates from children <15 ...
Anti-Bacterial Agents/therapeutic use, Carrier State, Cross-Sectional Studies, Nose/microbiology, Penicillin Resistance/physiology, Pharynx/microbiology, Pneumococcal Infections/epidemiology, Mozambique/epidemiology
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Invasive pneumococcal disease in children<5 years of age in rural Mozambique

Roca, A; Sigaúque, B; Quintó, Ll; Mandomando, L; Vallès, X; Espasa, M; Abacassamo, F; Sacarlal, J; Macete, E; Nhacolo, A; Levine, M; Alonso, P.
Trop. med. int. health; 11 (9), 2006
Objectivos Estimar a incidência e as características epidemiológicas do pneumococo invasivodoença (DPI) em crianças de <5 anos de idade residentes em uma área rural do sul de Moçambique.Métodos Como parte do manejo clínico de crianças internadas em Manhiçum Hospital Distrital,A vigilância pr...
Meningitis, Pneumococcal, Meningitis, Pneumococcal/epidemiology, Chloramphenicol/therapeutic use, Rural Population, Mozambique/epidemiology, Population Surveillance/methods, Pneumococcal Infections/epidemiology, Pneumonia/chemically induced, Rural Health, Anti-Infective Agents/therapeutic use
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