Cossa-moiane, idalécia;
Cossa, hermínio;
Bauhofer, adilson fernando loforte;
Chilaúle, jorfélia;
Guimarães, esperança lourenço;
Bero, diocreciano matias;
Cassocera, Marta;
Bambo, Miguel;
Anapakala, Elda;
Chissaque, Assucênio;
Sambo, Júlia;
Langa, Jerónimo Souzinho;
Manhique-Coutinho, Lena Vânia;
Fantinatti, maria;
Oliveira, Luis António Lopes;
Da-Cruz, alda maria;
de Deus, Nilsa.
Cryptosporidium is one of the most important causes of diarrhea in children less than 2 years of age. In this study, we report the frequency, risk factors and species of Cryptosporidium detected by molecular diagnostic methods in children admitted to two public hospitals in Maputo City, Mozambique. We st...
Cryptosporidiosis/epidemiology,
Cryptosporidium/isolation & purification,
Polymorphism, Restriction Fragment Length,
Cryptosporidiosis/parasitology,
Cryptosporidiosis/diagnosis,
Diarrhea, Infantile/epidemiology,
Polymerase Chain Reaction,
Diarrhea, Infantile/parasitology,
Risk Factors
Nhama, abel;
Nhamússua, lídia;
Macete, eusébio;
Bassat, quique;
Salvador, crizolgo;
Enosse, sónia;
Candrinho, baltazar;
Carvalho, eva;
Nhacolo, arsénio;
Chidimatembue, arlindo;
Saifodine, abuchahama;
Zulliger, rose;
Lucchi, naomi;
Svigel, samaly s;
Moriarty, leah f;
Halsey, eric s;
Mayor, alfredo;
Aide, pedro.
Background: Artemisinin-based combination therapy (ACT) has been the recommended first-line treatment for uncomplicated malaria in Mozambique since 2006, with artemether–lumefantrine (AL) and amodiaquine–artesunate (AS–AQ) as the first choice. To assess efficacy of currently used ACT, an in vivo...
Mozambique/epidemiology,
Artemether/administration & dosage,
Artesunate/administration & dosage,
Algorithms,
Malaria, Falciparum,
Malaria/drug therapy,
Lumefantrine,
Infections,
Efficacy/methods,
34628,
Patients,
Parasites,
Lost to Follow-Up,
Polymerase Chain Reaction,
Recurrence,
Safety,
Therapeutics,
Molecular Diagnostic Techniques
Mozambique, same as many other tropical countries, is at high risk of arthropod-borne virus (arbovirus) diseases and recently two dengue virus (DENV) outbreaks occurred in the northern part of the country. The occurrence of some important vector species, such as Aedes (Stegomyia) aegypti (Linnaeus) and A...
Salvador, Crizolgo;
Rafael, Bernardete;
Matsinhe, Francisco;
Matsinhe, Francisco;
Candrinho , Baltazar;
Muthemba , Rosália;
Carvalho, Eva;
Naueia, Eva;
Sacarlal, Jahit;
Namboze, Josephine;
Tiago , Armindo;
Warsame, Marian;
Enosse, Sónia.
he resistance of Plasmodium falciparum to anti-malarial drugs continues to challenge malaria control. We assessed the therapeutic efficacy and safety of artemether-lumefantrine (AL), the first-line treatment of uncomplicated P. falciparum malaria, in children under five years of age in Mozambique. We con...
Antimalarials/therapeutic use,
Artemisinins/therapeutic use,
Malaria/epidemiology,
d0109630,
d0200660,
d0161330,
Artemether, Lumefantrine Drug Combination,
Drug Combinations,
Ethanolamines/therapeutic use,
Fluorenes/therapeutic use,
Malaria, Falciparum/therapy,
Malaria, Falciparum/epidemiology,
Malaria, Falciparum/parasitology,
Plasmodium falciparum/genetics,
Polymerase Chain Reaction,
Mozambique/epidemiology
Oludele, John;
Lesko, Birgitta;
Gundane, Isabel Mahumane;
Nogueira, Fernanda de Bruycker;
Muianga, Argentina;
Ali, Sadia;
Mula, Flora;
Chelene, Emelda;
Falk, Kerstin I;
Santos, Flàvia Barreto dos;
Gudo, Eduardo Samo.
After the report of an outbreak of dengue virus serotype 2 in 2014 in Nampula and Pemba cities, northernMozambique, a surveillance system was established by the National Institute of Health. A study was performed during2015–2016 to monitor the trend of the outbreak and confirm the circulating serotype ...
Background: S. pneumoniae is the leading cause of acute bacterial meningitis (ABM) in children. Vaccination using the 10-valent conjugate vaccine (PCV-10) was recently introduced into the National Immunization Program in Mozambique, but data on serotype coverage of this vaccine formulation are scarce. In...
Anti-Bacterial Agents/pharmacology,
Pneumococcal Vaccines,
DNA, Bacterial/analysis,
Ceftriaxone/pharmacology,
Microbial Sensitivity Tests,
Drug Resistance, Multiple, Bacterial,
Epidemiological Monitoring,
Meningitis, Bacterial/epidemiology,
Meningitis, Bacterial/microbiology,
Meningitis, Bacterial/prevention & control,
Penicillins/pharmacology,
Pneumococcal Infections/immunology,
Pneumococcal Infections/microbiology,
Pneumococcal Vaccines/administration & dosage,
Streptococcus pneumoniae/classification,
Streptococcus pneumoniae/genetics,
Streptococcus pneumoniae/isolation & purification,
Streptococcus pneumoniae/radiation effects,
Polymerase Chain Reaction,
Mozambique/epidemiology
Em Moçambique a malária é considerada como sendo um dos mais importantes problemas de saúde pública, e uma das principais causas de morbilidade e mortalidade, especialmente em áreas remotas com pouco ou nenhum acesso a serviços públicos de saúde. O controlo vectorial da malaria é feito através...
Public Health,
Carbamates,
Anopheles,
Insecticides,
Acetylcholinesterase,
Culicidae,
Public Health Services,
Disease Susceptibility,
Remote Areas,
Polymerase Chain Reaction,
Mortality,
Morbidity,
Growth and Development,
Pyrethrins,
Malaria,
Incidence
Aguilar, Ruth;
Tejada, Ariel Magallon;
Achtman, Ariel H;
Moraleda, Cinta;
Joice, Regina;
Cisteró, Pau;
Suen, Connie S. N. Li Wai;
Nhabomba, Augusto;
Macete, Eusebio;
Mueller, Ivo;
Marti, Matthias;
Alonso, Pedro L;
Menéndez, Clara;
Schofield, Louis;
Mayor, Alfredo.
Plasmodium falciparum immature gametocytes are not observed in peripheral blood. However, gametocyte stages in organs such as bone marrow have never been assessed by molecular techniques, which are more sensitive than optical microscopy. We quantified P falciparum sexual stages in bone marrow (n = 174) a...
Anemia/parasitology,
Anemia/genetics,
Bone Marrow/pathology,
Bone Marrow/parasitology,
DNA, Protozoan/analysis,
Life Cycle Stages/genetics,
Malaria, Falciparum/diagnosis,
Malaria, Falciparum/genetics,
Malaria, Falciparum/parasitology,
Molecular Diagnostic Techniques,
Plasmodium falciparum/genetics,
Plasmodium falciparum/growth & development,
Plasmodium falciparum/isolation & purification,
Polymerase Chain Reaction,
Mozambique
Background: Plasmodium falciparum and HIV-1 infection cause substantial morbidity and mortality in sub-Saharan Africa. Increasing evidence suggests these two pathogens interact negatively when infecting the same individual.
Methods: A cross-sectional study among HIV-1 infected and uninfected populations...
Mayor, alfredo;
Casas, elisa serra;
Bardají, azucena;
Sanz, sergi;
Puyol, laura;
Cisteró, pau;
Sigauque, betuel;
Mandomando, inacio;
Aponte, john J;
Alonso, pedro L;
Menéndez, clara.
Background: Control of malaria in pregnancy remains a public health challenge. Improvements in its correct diagnosis and the adequacy of protocols to evaluate anti-malarial drug efficacy in pregnancy, are essential to achieve this goal.
Methods: The presence of Plasmodium falciparum was assessed by real-...
Malaria, Falciparum/epidemiology,
Merozoite Surface Protein 1,
Plasmodium falciparum,
Protozoan Proteins,
Pyrimethamine,
Malaria, Falciparum/therapy,
Malaria, Falciparum/parasitology,
Parasitemia/therapy,
Parasitemia/epidemiology,
Plasmodium falciparum/drug effects,
Plasmodium falciparum/genetics,
Plasmodium falciparum/isolation & purification,
Polymerase Chain Reaction,
Pregnancy Complications, Parasitic/therapy,
Pregnancy Complications, Parasitic/epidemiology,
Pregnancy Complications, Parasitic/parasitology
