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Safety and efficacy of dihydroartemisinin-piperaquine for intermittent preventive treatment of malaria in pregnant women with HIV from Gabon and Mozambique: a randomised, double-blind, placebo-controlled trial

González, Raquel; Nhampossa, Tacilta; Mombo-Ngoma, Ghyslain; Mischlinger, Johannes; Esen, Meral; Tchouatieu, André-Marie; Mendes, Anete; Figueroa-Romero, Antía; Zoleko-Manego, Rella; Lell, Bertrand; Lagler, Heimo; Stoeger, Linda; Dimessa, Lia Betty; El Gaaloul, Myriam; Sanz, Sergi; Méndez, Susana; Piqueras, Mireia; Sevene, Esperança; Ramharter, Michael; Saúte, Francisco; Menendez, Clara.
Lancet, Infect. dis.; 24 (5), 2024
For this randomised, double-blind, placebo-controlled clinical trial, women with HIV attending the first antenatal care clinic visit, resident in the study area, and with a gestational age up to 28 weeks were enrolled at five sites in Gabon and Mozambique. Participants were randomly assigned (1:1) to rec...
Antimalarials/administration & dosage, Artemisinins/administration & dosage, Double-Blind Method, Drug Combinations, Gabon, HIV Infections/complications, Malaria/therapy, Malaria/prevention & control, Piperazines, Pregnancy Complications, Quinolines/administration & dosage, Treatment Outcome, Trimethoprim, Sulfamethoxazole Drug Combination, Antimalarials/therapeutic use, Antimalarials/adverse effects, Artemisinins/adverse effects, Artemisinins/therapeutic use, Mozambique/epidemiology, Pregnancy Complications, Infectious/therapy, Pregnancy Complications, Infectious/prevention & control
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Effects of HIV infection on maternal and neonatal health in southern Mozambique: A prospective cohort study after a decade of antiretroviral drugs roll out

Gonzalez, Raquel; Ruperez, , Marı´a; Sevene, Esperanc¸a; Vala, Anifa; Maculuve, So´nia; Bulo, Helder; Nhacolo, Arse´nio; Mayor, Alfredo; Aponte, John J; Macete, Euse´bio; Medenendez, Clara.
PLos ONE; 12 (6), 2017
The HIV epidemic is concentrated in sub-Saharan Africa. However, limited information exists on its impact on women and infant's health since the introduction of antiretroviral drugs in this region, where health resources are often scarce. Methods: The effect of HIV infection on maternal health, birth ou...
Anti-HIV Agents/therapeutic use, HIV Infections/therapy, HIV Infections/epidemiology, Maternal Mortality, Infant, Newborn, Parturition, d0000680970, Pregnancy Complications, Infectious/therapy, Pregnancy Complications, Infectious/epidemiology, Pregnancy Outcome/epidemiology, Prospective Studies, Mozambique
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