Evaluation of the safety and efficacy of dihydroartemisinin-piperaquine for intermittent preventive treatment of malaria in HIV-infected pregnant women: protocol of a multicentre, two-arm, randomised, placebo-controlled, superiority clinical trial (MAMAH project)
BMJ Open; 11 (11), 2021
Introduction: Malaria infection during pregnancy is an important driver of maternal and neonatal health especially among HIV-infected women. Intermittent preventive treatment in pregnancy (IPTp) with sulphadoxine-pyrimethamine is recommended for malaria prevention in HIV-uninfected women, but it is contr...
Antimalarials/adverse effects, Artemisinins, Artesunate/administration & dosage, HIV Infections/prevention & control, Infectious Disease Transmission, Vertical/prevention & control, Malaria/prevention & control, Mozambique/epidemiology, Pregnancy Complications, Parasitic/chemically induced, Pregnancy Complications, Parasitic/prevention & control, Quinolines