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Clinical Performance of Self-Collected Nasal Swabs and Antigen Rapid Tests for SARS-CoV-2 Detection in Resource-Poor Settings

Sitoe, Nádia; Sambo, Júlia; Mabunda, Nédio; Nguenha, Neuza; Chilaúle, Jorfélia; Rafael, Julio; Macicane, Anésio; Chelene, Imelda; Viegas, sofia; Jani, Ilesh; Medenyanga, Chishamiso; Loquiha, Osvaldo; Sacks, Jillian.
Biomedicine; 10 (9), 2022
Background: In resource-poor countries, antigen-based rapid tests (Ag-RDTs) performed at primary healthcare and community settings improved access to SARS-CoV-2 diagnostics. However, the technical skills and biosafety requirements inherent to nasopharyngeal and oropharyngeal (OP) specimens limit the scal...
COVID-19 Serological Testing/trends, Primary Health Care/organization & administration, Real-Time Polymerase Chain Reaction/methods, Patients, COVID-19 Testing/methods, Hospitals, Mozambique/epidemiology
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Frequency of Pathogenic Paediatric Bacterial Meningitis in Mozambique: The Critical Role of Multiplex Real-Time Polymerase Chain Reaction to Estimate the Burden of DiseaseFrequency of Pathogenic Paediatric Bacterial Meningitis in Mozambique: The Critical Role of Multiplex Real-Time Polymerase Chain Reaction to Estimate the Burden of Disease

Nhantumbo, aquino albino; Cantarelli, vlademir vicente; Caireão, juliana; Munguambe, alcides moniz; Comé, charlotte elizabeth; Pinto, gabriela do carmo; Zimba, tomás francisco; Mandomando, inácio; Semá, cynthia baltazar; Gudo, eduardo samo; Moraes, milton ozório.
PLos ONE; 10 (9), 2015
Background: In Sub-Saharan Africa, including Mozambique, acute bacterial meningitis (ABM) represents a main cause of childhood mortality. The burden of ABM is seriously underestimated because of the poor performance of culture sampling, the primary method of ABM surveillance in the region. Low quality ce...
DNA, Bacterial/cerebrospinal fluid, DNA, Bacterial/genetics, Drug Resistance, Bacterial, Haemophilus influenzae/drug effects, Haemophilus influenzae/genetics, Haemophilus influenzae/isolation & purification, Meningitis, Bacterial/diagnosis, Meningitis, Bacterial/epidemiology, Meningitis, Bacterial/microbiology, Microbial Sensitivity Tests, Multivariate Analysis, Neisseria meningitidis/drug effects, Neisseria meningitidis/genetics, Neisseria meningitidis/isolation & purification, Real-Time Polymerase Chain Reaction/methods, Reproducibility of Results, Seasons, Sensitivity and Specificity, Severity of Illness Index, Streptococcus agalactiae/drug effects, Streptococcus agalactiae/genetics, Streptococcus agalactiae/isolation & purification, Streptococcus pneumoniae/drug effects, Streptococcus pneumoniae/genetics, Streptococcus pneumoniae/isolation & purification, Mozambique/epidemiology
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