Strydom, Amy;
Donato, celeste m;
Nyaga, martin m;
Boene, simone s;
Peenze, Ina;
Mogotsi, Milton T;
João, Eva D;
Munlela, benilde;
Potgieter, A. Christiaan;
Seheri, mapaseka L;
de Deus, Nilsa;
O’Neill, hester G.
This study presents whole genomes of seven bovine rotavirus strains from South Africa and Mozambique. Double-stranded RNA, extracted from stool samples without prior adaptation to cell culture, was used to synthesise cDNA using a self-annealing anchor primer ligated to dsRNA and random hexamers. The cDNA...
Introduction: Rotavirus A (RVA) is a leading cause of acute infant gastroenteritis in Mozambique, responsible for approximately 13,000 annual infant deaths in peri-urban and other areas. Aim: the present review aimed summarize the most relevant and recent literature regarding RVA infection in Mozambique....
Acácio, Sozinho;
Nhampossa, Tacilta;
Quintò, Llorenç;
Quintò, Llorenç;
Vubil, Delfino;
Garrine, Marcelino;
Bassat , Quique;
Farag, Tamer;
Panchalingam, Sandra;
Nataro, James P;
Kotloff , Karen L;
Levine, Myron M;
Tennant, Sharon M;
Alonso, Pedro L;
Mandomando, Inácio.
Rotavirus vaccines have been adopted in African countries since 2009, including Mozambique (2015). Disease burden data are needed to evaluate the impact of rotavirus vaccine. We report the burden of rotavirus-associated diarrhea in Mozambique from the Global Enteric Multicenter Study (GEMS) before vaccin...
Acácio, sozinho;
Mandomando, inácio;
Nhampossa, tacilta;
Quintó, llorenç;
Vubil, delfino;
Sacoor, charfudin;
Kotloff, karen;
Farag, tamer;
Nasrin, dilruba;
Macete, eusebio;
Levine, myron, m;
Alonso, pedro;
Bassat, quique.
In spite of very significant decreasing trends in the last three decades, childhood mortality remains unacceptably high globally, with 5.6 million children dying every year before reaching their 5th birthday, the majority of which in low and middle-income countries (LMIC) [1]. Diarrheal diseases still re...
Cryptosporidiosis/epidemiology,
Comorbidity,
Cryptosporidiosis/mortality,
Diarrhea/epidemiology,
Escherichia coli Infections/epidemiology,
Rotavirus Infections/mortality,
Survival Rate,
Diarrhea/microbiology,
Diarrhea, Infantile,
Diarrhea/mortality,
Mozambique
Strydom, amy;
Joao, eva dora;
Motanyane, lithabiso;
Nyanga, Martin m;
Potgieter, chistiaan;
Muamba, assa;
Mandomando, inacio;
Cassocera, Marta;
Deus, nilsa;
O'Neill, hester.
Rotavirus (RV) is an important enteric pathogen in the young of many mammalian and avian species. The virus belongs to the Reoviridae family and contains an 11-segmented double-stranded RNA (dsRNA) genome. The dsRNA segments encode six structural (VP1–4, 6 and 7) and six non-structural (NSP1–5/6) pro...
A doença diarreica na infância constitui um importante problema de saúde
pública em Moçambique. A infecção pelo Rotavirus é a uma das causas mais comum de diarreia
aguda grave a nível mundial, sendo a diarreia terceira causa de morbi-mortalidade infantil na
maioria d...
Child,
Diarrhea,
Disease,
Genotype,
Infections,
Rotavirus Infections,
Pediatrics,
Rotavirus,
Health,
Hospitals, General
Joao, eva dora;
Stroydon, amey;
Oneil g, hester;
Cumba, assa;
Cossecera, marta;
Acacio, sozinho;
Mandomando, inácio;
Motanyane, lithabiso;
Page, nicola;
Deus, nilsa de.
In Mozambique rotavirus (RV) was shown to be the greatest cause of acute diarrhoea in infants from 0 to 11 months, and in 2015, national rotavirus vaccination was introduced. As with other developing countries, there is very limited active strain characterisation. Rotavirus positive clinical specimens, c...
Gastroenteritis/virology,
Genotype,
Rotavirus Infections/virology,
Acute Disease,
Phylogeny,
Rotavirus/genetics,
Antigens, Viral/genetics,
Genetic Variation,
Gene Expression Regulation, Viral,
Mozambique,
Epitopes/genetics
A diarréia é uma importante causa de morbidade e mortalidade em todas as regiões do
mundo e entre todas as idades, ainda pouco se sabe sobre a fracção de episódios de
diarréia e óbitos de cada patógeno. Os rotavírus (RVs) foram designados como principal
causa de doença diarréica e desihidrata...
