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Susceptibility antibiotic screening reveals high rates of multidrug resistance of Salmonella, Shigella and Campylobacter in HIV infected and uninfected patients from Mozambique

Hlashwayo, Delfina F; Noormahomed, Emília V; Bahule, Leonilde; Benson, Constance A; Schooley, Robert T; Sigaúque, Betuel; Barrett, Kim E; Bila, Custódio G.
BMC infect. dis; 23 (225), 2023
Methods: We conducted antibiotic susceptibility testing on 157 stool isolates recovered from 129 patients aged between 0 and 80 years with diarrhea, including HIV infected (n = 68) and-uninfected individuals (n = 61), assisted at two health centers in Maputo city. The isolates comprised of 99 Salmonella,...
Agar, Anti-Bacterial Agents/pharmacology, Anti-Bacterial Agents/therapeutic use, Azithromycin, Bacteria, Campylobacter, Diarrhea/microbiology, Diarrhea/epidemiology, Drug Resistance, Bacterial, Drug Resistance, Multiple, Erythromycin, Gentamicins/pharmacology, Gentamicins/therapeutic use, HIV Infections/complications, HIV Infections/epidemiology, Microbial Sensitivity Tests, Mozambique/epidemiology, Salmonella, Sheep, Shigella, Tetracycline
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Antimicrobial Susceptibility and Mechanisms of Resistance in Shigella and Salmonella Isolates from Children under Five Years of Age with Diarrhea in Rural Mozambique

Mandomand, inacio; Espasa, mateu; Valles, xavier; Pons, maria J; Jaintilal, dinis; Mensa, laura; Macete, eusebio; Sacarlal, jahit; Sanz, Sergi; Sigauque, Betuel; Abacassamo, fatima; Alonso, pedro L; Ruiz, joaquim.
Antimicrob. agents chemother; 53 (6), 2009
The antimicrobial susceptibility and mechanisms of resistance of 109 Shigella and 40 Salmonella isolates from children with diarrhea in southern Mozambique were assessed. The susceptibility to seven antimicrobial agents was tested by disk diffusion, and mechanisms of resistance were searched by PCR or co...
Anti-Bacterial Agents/pharmacology, Diarrhea/microbiology, Microbial Sensitivity Tests, Amplified Fragment Length Polymorphism Analysis, Shigella/genetics
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Epidemiology and clinical presentation of shigellosis in children less than five years of age in rural Mozambique

Mandomando, inácio; Espasa, mateu; Vallès, xavier; Sigaúque, betuel; Sanz, sergi; Sacarlal, jahit; Macete, eusébio; Abacassamo, fátima; Ruiz, joaquim; Gascon, joaquim; Kotloff, karen L; Levine, myron.
Pediatr. infect. dis. j; 26 (11), 2007
Rectal swabs were collected from 1354 children <5 years of age with diarrhea attending Manhiça District Hospital and from 227 healthy community controls. Shigellosis incidence was high among children aged 12-47 months (488.4/10(5) child-years at risk). Fever and dysentery were prominent clinical finding...
Diarrhea/epidemiology, Diarrhea/microbiology, Dysentery, Bacillary/epidemiology, Dysentery, Bacillary/microbiology, Dysentery, Bacillary/physiopathology, Shigella/classification, Shigella/isolation & purification, Mozambique/epidemiology
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