Invasive bacterial disease trends and characterization of group B streptococcal isolates among young infants in southern Mozambique, 2001-2015
PLoS One; 13 (1), 2018
Maternal group B streptococcal (GBS) vaccines under development hold promise to prevent GBS disease in young infants. Sub-Saharan Africa has the highest estimated disease burden, although data on incidence and circulating strains are limited. We described invasive bacterial disease (IBD) trends among inf...
Streptococcal Infections/epidemiology, Mozambique/epidemiology, Virulence/genetics, Penicillin Resistance, Bacterial Infections/epidemiology, Genome, Bacterial, Immunity, Maternally-Acquired, Incidence, Infant, Newborn, Microbial Sensitivity Tests, Multiplex Polymerase Chain Reaction, Penicillin Resistance/genetics, Penicillin-Binding Proteins/genetics, Point Mutation, Streptococcal Infections/microbiology, Streptococcal Infections/prevention & control, Streptococcal Vaccines/pharmacology, Streptococcus agalactiae/drug effects