Intermittent Preventive Treatment of Malaria in Pregnancy with Mefloquine in HIV-Infected Women Receiving Cotrimoxazole Prophylaxis: A Multicenter Randomized Placebo-Controlled Trial
PloS med; 14 (160), 2014
Background: Intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) is recommended for malaria prevention in HIV-negative pregnant women, but it is contraindicated in HIV-infected women taking daily cotrimoxazole prophylaxis (CTXp) because of potential added risk of adve...
Antimalarials/administration & dosage, Double-Blind Method, Follow-Up Studies, HIV Infections/diagnosis, HIV Infections/drug therapy, HIV Infections/epidemiology, Infectious Disease Transmission, Vertical/prevention & control, Malaria/diagnosis, Malaria/epidemiology, Malaria/prevention & control, Mefloquine/administration & dosage, Pregnancy Complications, Infectious/diagnosis, Pregnancy Complications, Infectious/epidemiology, Pregnancy Complications, Infectious/prevention & control, Pregnancy Complications, Parasitic/diagnosis, Pregnancy Complications, Parasitic/epidemiology, Pregnancy Complications, Parasitic/prevention & control, Pregnancy Outcome, Mozambique/epidemiology, Tanzania/epidemiology, Kenya/epidemiology, Trimethoprim, Sulfamethoxazole Drug Combination/administration & dosage