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Evaluation of the multidrug-resistant tuberculosis surveillance system in Maputo City, Mozambique in the period 2017-2018

Balate, dionísia alfredo; Manhiça, ivan; Macuacua, bachir; José, benedita; Banze, denise; Langa, josé carlos; Baltazar, cynthia semá; Sacarlal, jahit; Rossetto, erika valeska; Khosa, celso.
Pan Afr. med. j; 41 (), 2022
Introduction: multidrug-resistant tuberculosis (MDR-TB) remains a public health problem worldwide. In Mozambique, cases of MDR-TB have increased annually. In 2018, 1,206 cases were reported, as compared to 943 cases in 2017. The aim of this study was to assess the surveillance system for multidrug-resist...
Antitubercular Agents/therapeutic use, Databases, Factual, Tuberculosis, Tuberculosis, Multidrug-Resistant, Mycobacterium tuberculosis, Mozambique, Tuberculosis, Multidrug-Resistant/diagnosis, Tuberculosis, Multidrug-Resistant/therapy, Tuberculosis, Multidrug-Resistant/epidemiology
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Detection of katG and inhA mutations to guide isoniazid and ethionamide use for drug-resistant tuberculosis

Bollela, VR; Namburete, EI; Feliciano, CS; Macheque, D; Harrison, LH; Caminero, JA.
Int J Tuberc Lung Dis; 20 (8), 2016
Background: Depending on the presence of mutations that determine isoniazid (INH) susceptibility (katG and inhA), Mycobacterium tuberculosis may be susceptible to high doses of INH or ethionamide (ETH). Objective: To describe the INH resistance profile and association of katG mutation with previous INH ...
Antitubercular Agents/therapeutic use, Diagnosis, Tuberculosis, Multidrug-Resistant/drug therapy, Mycobacterium tuberculosis, DNA Mutational Analysis, Tuberculosis, Multidrug-Resistant/diagnosis
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