Introduction
Mozambique has a high burden of Tuberculosis (TB) with an incidence of 368 per 100,000 population in 2020, coupled with a low all-form TB detection rate. The COVID-19 pandemic has exacerbated delays in timely diagnosis and treatment of new TB cases. Promoting active TB case finding is a nati...
Barilar, ivan;
Fernando, Tatiana;
Utpatel, christian;
Abujate, cláudio;
Madeira, Carla, M;
José, benedita;
Mutaquiha, claudia;
Kranzer, katharina;
Niemann, tanja.
Background
In 2021, an estimated 4800 people developed rifampicin-resistant tuberculosis in Mozambique, 75% of which went undiagnosed. Detailed molecular data on rifampicin-resistant and multidrug-resistant (MDR) tuberculosis are not available. Here, we aimed at gaining precise data on the determinants o...
Antitubercular Agents/pharmacology,
Antitubercular Agents/therapeutic use,
Fluoroquinolones/pharmacology,
Tuberculosis, Multidrug-Resistant,
Mozambique,
Mycobacterium tuberculosis/genetics,
Rifampin/therapeutic use,
Tuberculosis/therapy,
Tuberculosis, Multidrug-Resistant/therapy
Evans, denise;
Rensburg, craig van;
Ivanova, olena;
Rieß, friedrich;
Siroka, andrew;
Sillah, abdou K;
Ntinginya, nyanda elias;
Jani, ,ilesh;
Sathar, farzana;
Rosen, sydney;
Sanne, ian;
Rachow, andrea.
The WHO developed a generic 'TB patient cost survey' tool and a standardized approach to assess the direct and indirect costs of TB incurred by patients and their households, estimate the proportion of patients experiencing catastrophic costs, and measure the impact of interventions to reduce patient cos...
This study evaluated a National External Quality Scheme Program for early infant diagnosis of HIV. Fourteen laboratory technicians participated, and nine testing panel cycles were sent between 2011 and 2014. The response rate was 100% for the first eight panels, and the number of technicians with a test ...
Background: Mozambique is among the highest tuberculosis, tuberculosis–HIV and multidrug-resistant-tuberculosis burden countries. Although molecular technologies are available in-country, mycobacterial isolation through culture remains an important tool for tuberculosis diagnostics and drug susceptibil...
Manhiça, ivan;
Mutaquiha, cláudia;
Zindoga, pereira;
Cowan, jamie;
José, benedita;
Pacala, domingas;
Mutemba, criménia;
Machai, maria josé pires;
Azam, khalide;
Ruano, maria.
O surgimento de resistência aos fármacos usados para tratar a tuberculose (TB), particularmente a Tuberculose Multirresistente (TB-MR), tornou-se um problema de saúde pública em vários
países e, um sério obstáculo na luta contra Tuberculose, razão pela qual a OMS recomenda desde o ano 2000 uma a...
Orlando, s;
Triulzi, i;
Ciccacci, f;
Palla, i;
Palombi, l;
Marazzi, m c;
Giuliano, m;
Floridia, m;
Mancinelli, s;
Mutemba, e;
Turchetti, g.
Background: Tuberculosis (TB) represents the ninth leading cause of death worldwide. In 2016 are estimated 1.3 million TB deaths among HIV negative people and an additional 374,000 deaths among HIV positive people. In 2016 are estimated 1.4 million new cases of TB in people living with HIV (PLHIV), 74% o...
Comorbidity,
Cost-Benefit Analysis,
Delayed Diagnosis,
Diagnostic Tests, Routine/methods,
HIV Infections/diagnosis,
HIV Infections/epidemiology,
HIV Infections/therapy,
Mass Screening/methods,
Reproducibility of Results,
Tuberculosis/epidemiology,
Tuberculosis/diagnosis,
Tuberculosis/therapy,
Mozambique/epidemiology,
High-Throughput Screening Assays/economics,
Mozambique
Background
Studies have been conducted in developing countries using SMS to communicate with patients to reduce the number of missed appointments and improve retention in treatment, however; very few have been scaled up. One possible reason for this could be that patients or staff are dissatisfied with t...
Objectives: We describe nevirapine and efavirenz exposure on and off tuberculosis treatment and consequences for virological efficacy and tolerance in patients included in the ANRS 12146/12214-CARINEMO trial.
Methods: Participants were randomly selected to receive either nevirapine at 200 mg twice daily...
Alkynes,
Antiretroviral Therapy, Highly Active/methods,
Antitubercular Agents/therapeutic use,
Benzoxazines/therapeutic use,
Cyclopropanes,
HIV Infections/therapy,
Drug Tolerance,
Anti-HIV Agents/therapeutic use,
Infections/complications,
Nevirapine/therapeutic use,
Tuberculosis/therapy,
Tuberculosis/complications,
Treatment Outcome,
Mozambique
