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Stability of HIV-1 Nucleic Acids in cobas Plasma Separation Card for Viral Load Measurement

Vubil, adolfo; Nhachigule, carina; Zicai, ana flora; Meggi, bindiya; Costa, paulino da; Mabunda, nédio; Viegas, sofia; Sitoe, nádia; Jani, ilesh.
Am. j. clin. pathol; 158 (1), 2022
Objectives: Our study aimed to evaluate the stability of human immunodeficiency virus 1 (HIV-1) RNA on cobas plasma separation card (PSC) specimens for viral load (VL) testing after being exposed to varied temperatures and storage times. Methods: For this purpose, venous PSC specimens were collected and ...
HIV Infections, Nucleic Acids, HIV-1/genetics, RNA, Viral/genetics, Viral Load/methods, Mozambique
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Viral load assay performs comparably to early infant diagnosis assay to diagnose infants with HIV in Mozambique: a prospective observational study

Vubil, adolfo; Nhachigule, carina; Loquiha, osvaldo; Meggi, bindiya; Mabunda, nedio; Bollinger, timothy; Sacks, jilian a; Jani, llesh; Vojnov, lara.
J. int. aids soc; 23 (), 2020
Introduction: Viral load testing is essential to manage HIV disease, especially in infants and children. Early infant diagnosis (EID) is performed using nucleic-acid testing in children under 18 months. Resource-limited health systems face severe challenges to scale-up both viral load and EID to unpreced...
HIV Infections/diagnosis, HIV Infections/virology, HIV-1/genetics, HIV-1/isolation & purification, HIV-1/physiology, Infant, Newborn, Diseases/diagnosis, Infant, Newborn, Diseases/virology, Mozambique, Sensitivity and Specificity, Prospective Studies, Viral Load/methods, Viremia/diagnosis, Viremia/virology
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Evaluation of the Whole-Blood Alere Q NAT Point-of-Care RNA Assay for HIV-1 Viral Load Monitoring in a Primary Health Care Setting in Mozambique

Jani, ilesh, v; Meggi, bindiya; Vubil, adolfo; Bhatt, nilesh; Tobaiwa, ocean; Quevedo, jorge, i; Loquiha, osvaldo; Lehe, jonathan, d; Vojnov, lara; Peter, trevor, f.
J. clin. microbiol; 54 (4), 2016
Viral load testing is the WHO-recommended monitoring assay for patients on HIV antiretroviral therapy (ART). Point-of-care (POC) assays may help improve access to viral load testing in resource-limited settings. We compared the performance of the Alere Q NAT POC viral load technology (Alere Technologies,...
HIV Infections/virology, Primary Health Care, Mozambique, Primary Health Care/methods, Drug Monitoring/methods, HIV Infections/therapy, RNA, Viral/blood, Sensitivity and Specificity, Viral Load/methods
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