Resultados: 49

Safety of incidental exposure to the novel oral poliovirus vaccine type 2 in pregnancy: A longitudinal observational study in Mozambique, 2022-2023

Vaccine; 15 (), 2024
To minimize the risk of vaccine-derived poliovirus emergences, the novel oral poliovirus vaccine type 2 (nOPV2), was bioengineered to have increased genetic stability compared to Sabin OPV and recommended for outbreak response Emergency Use Listing by WHO. Although pregnant women are not a target populat...

B-cell immunity and vaccine induced antibody protection reveal the inefficacy of current vaccination schedule in infants with perinatal HIV-infection in Mozambique, Africa

EBioMedicine; 93 (104666), 2023
Despite antiretroviral treatment (ART), immune dysfunction persists in children with perinatal HIV infection (HEI). Here we investigated the impact of HIV status on maternal antibody (Ab) passage, long-term vaccine induced immunity and B-cell maturation. Methods: 46 HIV Exposed Uninfected (HEU), 43 HEI,...

Increased peripartum mortality associated with maternal subclinical malaria in Mozambique

Malar. j. (Online); 22 (182), 2023
Background: Plasmodium falciparum infection in pregnant women in sub-Saharan Africa is often asymptomatic. As these forms of malaria are often submicroscopic and difficult to diagnose by conventional methods (microscopy and/or rapid diagnostic test), diagnosis requires the use of molecular techniques suc...

Attitudes and perceptions towards postpartum contraceptive use among seroconcordant partners with HIV in rural Mozambique: a qualitative study

Background Postpartum contraceptive uptake reduces short interpregnancy intervals, unintended pregnancies, and their negative sequalae: poor maternal and fetal outcomes. Healthy timing and spacing of pregnancy in people living with HIV (PLHIV) also allows time to achieve viral suppression to reduce paren...

Study design and rationale for the PAASIM project: a matched cohort study on urban water supply improvements and infant enteric pathogen infection, gut microbiome development and health in Mozambique

BMJ; 3 (13), 2023
Introduction: Despite clear linkages between provision of clean water and improvements in child health, limited information exists about the health impacts of large water infrastructure improvements in low-income settings. Billions of dollars are spent annually to improve urban water supply, and rigorou...

Maternal and child health care service disruptions and recovery in mozambique after cyclone idai: an uncontrolled interrupted time series analysis

Glob. health sci. pract; 15 (1), 2022
Introduction: Climate change-related extreme weather events have increased in frequency and intensity, threatening people’s health, particularly in places with weak health systems. In March 2019, Cyclone Idai devastated Mozambique’s central region, causing infrastructure destruction, population displ...

Burden of malaria in pregnancy among adolescent girls compared to adult women in 5 sub-Saharan African countries: A secondary individual participant data meta-analysis of 2 clinical trials

PloS med; 19 (9), 2022
Malaria is among the top causes of death in adolescent girls (10 to 19 years) globally. Adolescent motherhood is associated with increased risk of adverse maternal and neonatal outcomes. The interaction of malaria, adolescence, and pregnancy is especially relevant in malaria endemic areas, where rates of...

Ansiedade, depressão e suporte social em gestantes atendidas na atenção primária na cidade de nampula em Moçambique
Anxiety, depression and social support in pregnant women attending primary care in the city of nampula in Mozambique

A mulher grávida, ao se deparar com as transformações físicas, hormonais, psíquicas e de inserção social, vivencia a manifestação de sintomas de transtornos mentais, no pré-natal, dentre eles a ansiedade e a depressão. O objetivo geral desta pesquisa foi avaliar a presença de indicadores de a...

Known HIV status among adolescent women attending antenatal care services in Eswatini, Ethiopia and Mozambique

Reprod. health; 18 (90), 2021
Antenatal care (ANC) clinics remain important entry points to HIV care for pregnant women living with HIV—including adolescents. Prior knowledge of their HIV status at ANC enrollment is crucial to providing services for prevention of mother-to-child transmission (PMTCT) of HIV. We examined known HIV st...

Covid-19 pandemic impact on maternal and child health services access in Nampula, Mozambique: a mixed methods research

Background: The Covid-19 pandemic has so far infected more than 30 million people in the world, having major impact on global health with collateral damage. In Mozambique, a public state of emergency was declared at the end of March 2020. This has limited people’s movements and reduced public services,...