Castro, Lucia Carratala;
Ssengooba, Willy;
Kay, Alex;
Acácio, Sozinho;
Ehrlich, Joanna;
DiNardo, Andrew R;
Shiba, Shiba;
Nsubuga, Joachim K;
Munguambe, Shilzia;
Cervera, Belén Saavedra;
Manjate, Patricia;
Mulengwa, Durbbin;
Sibandze, Busizwe;
Ziyane, Mangaliso;
Kasule, George;
Mambuque, Edson;
Sekadde, Moorine Penninah;
Wobudeya, Eric;
Joloba, Moses L;
Heyckendorf, Jan;
Lange, Christoph;
Hermans, Sabine;
Mandalakas, Anna;
Basteiro, Alberto L García;
Varela, Elisa Lopez.
Background: Tuberculosis (TB) is a major cause of mortality worldwide. Children and people living with HIV (PLHIV) have an increased risk of mortality, particularly in the absence of rapid diagnosis. The main challenges of diagnosing TB in these populations are due to the unspecific and paucibacillary di...
Infecções por HIV/complicações,
Mycobacterium tuberculosis,
Tuberculose/diagnóstico,
Tuberculose Pulmonar/diagnóstico,
Infecções por HIV/diagnóstico,
Estudos Multicêntricos como Assunto,
Estudos Prospectivos,
Sensibilidade e Especificidade,
Essuatíni,
Moçambique,
Uganda
Olbrich, laura;
Verghese, Valsan, P;
Smith, zoe franckling;
Sabi, issa;
Ntinginya, Nyanda E;
Mfinanga, alfred;
Banze, denise;
Viegas, sofia omar;
Khosa, celso;
Semphere, robina.
Background Childhood tuberculosis remains a major cause of morbidity and mortality in part due to missed diagnosis. Diagnostic methods with enhanced sensitivity using easy-to-obtain specimens are needed. We aimed to assess the diagnostic accuracy of the Cepheid Mycobacterium tuberculosis Host Response pr...
A Tuberculose Extrapulmonar é uma infecção crónica causada pelo Mycobacterium tuberculosis, que afecta qualquer órgão fora da árvore brônquica–pulmonar, sendo mais incidente em países de baixa renda como Moçambique devido a prevalência aumentada de imunodeficiência grave por enfermidades e ...
Tuberculosis (TB) and malnutrition are important causes of morbidity and mortality in children in the developing world.
Aims
To assess the prevalence of pulmonary TB in severely malnourished children and evaluate TB detection using the urine lipoarabinomannan antigen assay (TB-LAM).
Methods
A retrospec...
Khosa1,2*, celso;
Bhatt1, nilesh;
Massango1, isabel;
Azam1,2, khalide;
Saathoff3,4, elmar;
Bakuli3, abhishek;
Riess3, friedrich;
Ivanova3, olena;
Hoelscher2,3,4, michael;
Rachow2,3,4, andrea.
Pulmonary tuberculosis (PTB) is frequently associated with chronic respiratory impairment despite
microbiological cure. There are only a few clinical research studies that describe the course, type and severity as
well as associated risk factors for lung impairment (LI) in TB patients....
In this comparative biomarker study, we analysed 1768 serial sputum samples from 178 patients at 4 sites in Southeast Africa. We show that tuberculosis Molecular Bacterial Load Assay (TB-MBLA) reduces time-to-TB-bacillary-load-result from days/weeks by culture to hours and detects early patient treatment...
Background: Pulmonary tuberculosis (PTB) is frequently associated with chronic respiratory impairment despite microbiological cure. There are only a few clinical research studies that describe the course, type and severity aswell as associated risk factors for lung impairment (LI) in TB patients.
Methods...
Background: In-hospital logistic management barriers (LMB) are considered to be important risk factors for delays in TB diagnosis and treatment initiation (TB-dt), which perpetuates TB transmission and the development of TB morbidity and mortality. We assessed the contribution of hospital auxiliary worke...
Terapêutica,
Pessoal de Laboratório,
Pacientes,
Mortalidade,
Morbidade,
Escarro,
Fatores de Risco,
HIV,
Modelos Logísticos,
Diagnóstico,
51607,
Tuberculose Pulmonar,
Cooperação e Adesão ao Tratamento
Rachow, andrea;
Ivanova, olena;
Wallis, robert;
Charalambous, Salome;
Jani, ilesh;
Bhatt, Nilesh;
Kampmann, beate;
Sutherland, Jayne;
Ntinginya, Nyanda, E;
Evans, Denise;
Lönnroth, knut;
Niemann, Stefan.
Background: Up to fifty percent of microbiologically cured tuberculosis (TB) patients may be left with permanent, moderate or severe pulmonary function impairment. Very few studies have systematically examined pulmonary outcomes in patients to understand the pathophysiologic basis and long-term socio-eco...
Antituberculosos/uso terapêutico,
Incidência,
Tuberculose Pulmonar,
Patogenesia Homeopática,
Fatores de Risco,
Qualidade de Vida,
Testes de Função Respiratória,
Resultado do Tratamento,
Tuberculose Resistente a Múltiplos Medicamentos/terapia,
Tuberculose Resistente a Múltiplos Medicamentos/epidemiologia,
Tuberculose Resistente a Múltiplos Medicamentos/fisiopatologia,
Tuberculose Pulmonar/terapia,
Tuberculose Pulmonar/epidemiologia,
Tuberculose Pulmonar/fisiopatologia
Floridia, Marco;
Ciccacci, Fausto;
Andreotti, Mauro;
Hassane, Archa;
Sidumo, Zita;
Magid, Nurja A;
Sotomane, Horacio;
David, Muhlavasse;
Mutemba, Elsa;
Cebola, Junia;
Mugunhe, Remigio José;
Riccardi, Fabio;
Marazzi, Maria Cristina;
Giuliano, Marina;
Palombi, Leonardo;
Mancinelli, Sandro.
Tuberculosis is a major health concern in several countries, and effective diagnostic algorithms for use in human
immunodeficiency virus (HIV)–positive patients are urgently needed.
Methods. At prescription of antiretroviral therapy, all patients in 3 Mozambican health centers were screened for tubercu...
Algoritmos,
Terapia Antirretroviral de Alta Atividade,
Antituberculosos,
Infecções por HIV/tratamento farmacológico,
Lipopolissacarídeos,
Técnicas de Diagnóstico Molecular,
Moçambique,
Mycobacterium tuberculosis,
Prevalência,
Sensibilidade e Especificidade,
Tuberculose Pulmonar/diagnóstico,
Escarro
