Background: The objective was to study the seasonal effect on the spatial distribution of the incidence of malaria in children under 10 years old living in the Manhiça district, Mozambique.
Methods: The data of the clinical malaria incidence were obtained from a study of two cohorts of children followed...
Quelhas, diana;
Casas, elisa serra;
Quinto, llorenç;
Puyol, laura;
Nhampossa, tacilta;
Macete, eusebio;
Aide, pedro;
Mayor, alfredo;
Mandomando, inacio;
Sanz, sergio;
Aponte, john J;
Chitnis, chetan E;
Chauhan, virander S;
Alonso, pedro L;
Dobano, carlota;
Menendez, clara.
We evaluated the impact of intermittent preventive treatment in infants (IPTi) with sulfadoxine-pyrimethamine (SP), which was given at ages 3, 4, and 9 months through the Expanded Program on Immunization (EPI), on the development of antibody responses to Plasmodium falciparum in Mozambique. Immunoglobuli...
Anticorpos Antiprotozoários/sangue,
Anticorpos Antiprotozoários/imunologia,
Anticorpos Antiprotozoários/genética,
Antimaláricos/administração & dosagem,
Antimaláricos/uso terapêutico,
Malária Falciparum/imunologia,
Malária Falciparum/prevenção & controle,
Plasmodium falciparum/imunologia,
Pirimetamina/administração & dosagem,
Moçambique,
Proteínas Recombinantes/genética,
Proteínas Recombinantes/imunologia
Background: Endomyocardial fibrosis is the most common restrictive cardiomyopathy worldwide. It has no specific treatment and carries a poor prognosis, since most patients present with advanced heart failure. On the basis of clinical series, regional variations in distribution have been reported within s...
In late 2002, the health authorities of Mozambique implemented sulphadoxine-pyrimethamine (SP)/amodiaquine (AQ) as first-line treatment against uncomplicated falciparum malaria. In 2004, this has been altered to SP/artesunate in line with WHO recommendations of using Artemisinin Combination Therapies (AC...
Pirimetamina/farmacologia,
Proteínas de Protozoários/genética,
Malária Falciparum/epidemiologia,
d0161330,
d0138120,
Moçambique/epidemiologia,
Ligases,
Combinação de Medicamentos,
Resistência a Medicamentos/genética,
Combinação Ezetimiba e Simvastatina/uso terapêutico,
Pirimetamina/provisão & distribuição,
Preparações Farmacêuticas,
Haplótipos/genética,
Malária Falciparum/terapia,
Malária Falciparum/parasitologia,
Plasmodium falciparum/efeitos da radiação,
Plasmodium falciparum/isolamento & purificação,
Proteínas de Protozoários/normas,
Sulfadoxina/farmacologia
Técnicas de Laboratório Clínico,
Atenção Primária à Saúde,
Moçambique,
HIV,
Síndrome da Imunodeficiência Adquirida,
População Rural,
Serviços de Saúde Materna,
Avaliação do Impacto na Saúde,
Tuberculose,
Malária,
32395,
Interpretação Estatística de Dados,
Garantia da Qualidade dos Cuidados de Saúde,
Sistema de Vigilância em Saúde,
Monitoramento Epidemiológico,
Gestantes,
Registros Públicos de Dados de Cuidados de Saúde
Mayor, Alfredo;
Serra-Casas, Elisa;
Sanz, Sergi;
Aponte, João J;
Machete, eusebio;
Mandomando, Inácio;
Puyol, Laura;
Berzosa, Pedro;
Dobanã, Carlota;
Aide, pedro;
Sacarlal, jahit;
Benito, Agustín;
Alonso, Pedro;
Menendéz, Clara.
Background. Intermittent preventive treatment in infants (IPTi) with sulfadoxine-pyrimethamine (SP) is a po tential malaria control strategy. There is concern about the impact that increasing in vivo resistance to SP has on the efficacy of IPTi, as well as about the potential contribution of IPTi to incr...
Roca, anna;
Quinto , llorenc;
Abacassamo, fatima;
Morais, luis;
Valle, xavier;
Espasa, mateu;
Sigauque, betuel;
Sacarla, jahit;
Macete, eusebio;
Nhacolo, ariel;
Mandomando, inacio;
Levine, myron M;
Alonso, pedro L.
Objective: To measure the disease burden and epidemiological characteristics of invasive Haemophilus influenzae in rural Mozambican children. Methods: As part of the clinical management of children admitted to Manhiça District Hospital, blood and cerebrospinal fluid samples were collected between May 20...
Bassat, quique;
Guinovart, caterina;
Sigaúque, betuel;
Aide, pedro;
Sacarlal, jahit;
Nhampossa, tacilta;
Bardají, azucena;
Nhacolo, ariel 2,;
Macete, eusébio;
Mandomando, inácio;
Aponte, john J;
Alonso, pedro L;
Menéndez, clara.
Background: Characterization of severe malaria cases on arrival to hospital may lead to early recognition and improved management. Minimum community based-incidence rates (MCBIRs) complement hospital data, describing the malaria burden in the community. Methods: A retrospective analysis of all admitted m...
Malária Falciparum/epidemiologia,
Malária Falciparum/mortalidade,
Malária Falciparum/fisiopatologia,
Malária Falciparum/terapia,
Análise Multivariada,
Plasmodium falciparum/isolamento & purificação,
Moçambique/epidemiologia,
Modelos Logísticos,
Fatores de Risco,
Estações do Ano,
Hospitalização
Guinovart, caterina;
Bassat, quique;
Sigaúque, betuel;
Aide, pedro;
Sacarlal, jahit;
Nhampossa, tacilta;
Bardají, azucena;
Nhacolo, ariel;
Macete, eusébio;
Mandomando, inácio;
Aponte, john J;
Menéndez, clara;
Alonso, pedro L.
Background: Malaria represents a huge burden for the health care services across Africa. Describing malaria attending health services contributes to quantify the burden and describe the epidemiology and clinical presentation.
Methods: Retrospective analysis of data collected through the Manhiça morbidit...
Bardají, azucena;
Sigauque, betuel;
Bruni, mlaia;
Romagosa, cleofé;
Sanz, sergi;
Mabunda, samuel;
Mandomando, inacio;
Aponte, john;
Sevene, esperança;
Alonso, pedro L;
Menéndez, clara.
Background: There is a widespread notion, based on limited information, that in areas of stable malaria transmission most pregnant women with Plasmodium falciparum infection are asymptomatic. This study aim to characterize the clinical presentation of malaria in African pregnant women and to evaluate the...
