Voronin, yegor;
Jani, ilesh;
Graham, barney, s;
Cunningham, coleen, k;
Mofenson, lynne, m;
Musoke, philippa, m;
Permar, sallie, r;
Scarlatti, gabriella.
Globally, 150,000 new paediatric human immunodeficiency virus type 1 (HIV-1) infections occurred in 2015. There remain complex challenges to the global elimination of paediatric HIV-1 infection. Thus, for the global community to achieve elimination of new paediatric HIV-1 infections, innovative approache...
HIV-1,
HIV-1/imunologia,
Vacinas contra a AIDS/administração & dosagem,
Anticorpos Anti-HIV,
Vacinas contra a AIDS/imunologia,
Infecções por HIV,
Anticorpos Neutralizantes/imunologia,
Anticorpos Anti-HIV/imunologia,
Infecções por HIV/imunologia,
Infecções por HIV/prevenção & controle,
Infecções/virologia,
Transmissão Vertical de Doenças Infecciosas/prevenção & controle
Jordan, M Michael;
Penazzato, Martina;
Cournil, Amandine;
Vubil, Adolfo;
Jani, Ilesh;
Hunt, Gilian;
Maphalala, Gudo;
Carmona, Sergio;
Mthethwa, Nobuhle;
Watera, Christine;
Kaleebu, Pontiano;
Musanhu, Christine Chaknyuka;
Mtapuri-Zinyowera, Sekasai;
Dzangare, Janet;
Peeters, Martine;
Yang, Chunfu;
Parkin, Iveil;
Bertagnolio, Silvia.
Background. Programs for the prevention of mother-to-child transmission (PMTCT) of human immunodeficiency virus (HIV) have been scaled up in many low- and middle-income countries. However, HIV drug resistance (HIVDR) data among HIV-1– infected young children remain limited.
Methods. Surveys of pretreat...
Background: Concerning gaps in the HIV care continuum compromise individual and population health. We evaluated a combination intervention strategy (CIS) targeting prevalent barriers to timely linkage and sustained retention in HIV care in Mozambique.
Methods and findings: In this cluster-randomized tria...
Fármacos Anti-HIV/administração & dosagem,
Análise por Conglomerados,
Terapia Combinada,
Intervenção Médica Precoce/métodos,
Seguimentos,
Infecções por HIV/diagnóstico,
HIV-1/efeitos dos fármacos,
Comportamentos Relacionados com a Saúde,
Motivação,
Cooperação do Paciente,
Epidemiologia,
Terapêutica,
Moçambique,
Infecções por HIV/terapia
Floridia, Marco;
Ciccacci, Fausto;
Andreotti, Mauro;
Hassane, Archa;
Sidumo, Zita;
Magid, Nurja A;
Sotomane, Horacio;
David, Muhlavasse;
Mutemba, Elsa;
Cebola, Junia;
Mugunhe, Remigio José;
Riccardi, Fabio;
Marazzi, Maria Cristina;
Giuliano, Marina;
Palombi, Leonardo;
Mancinelli, Sandro.
Tuberculosis is a major health concern in several countries, and effective diagnostic algorithms for use in human
immunodeficiency virus (HIV)–positive patients are urgently needed.
Methods. At prescription of antiretroviral therapy, all patients in 3 Mozambican health centers were screened for tubercu...
Algoritmos,
Terapia Antirretroviral de Alta Atividade,
Antituberculosos,
Infecções por HIV/tratamento farmacológico,
Lipopolissacarídeos,
Técnicas de Diagnóstico Molecular,
Moçambique,
Mycobacterium tuberculosis,
Prevalência,
Sensibilidade e Especificidade,
Tuberculose Pulmonar/diagnóstico,
Escarro
Introduction: The scale-up of effective HIV viral load (VL) testing is an urgent public health priority. Implementation of testing is supported by the availability of accurate, nucleic acid based laboratory and point-of-care (POC) VL technologies and strong WHO guidance recommending routine testing to id...
Martins-Fonteyn, Emilia;
Loquiha, Osvaldo;
Baltazar, Cynthia;
Thapa, Subash;
University of California, San Francisco – USA, of Global Health Sciences;
Raimundo, Ines;
Hens, Niel;
Aerts, Marc;
Meulemans, Herman;
Degomme, Olivier;
Wouters, Edwin.
Background: Information dealing with social and behavioural risk factors as well as their mechanisms among
Mozambican migrants working in South African mines remains undocumented. This study aims to understand the
various factors influencing HIV-related risk behaviours and the resulting HIV positive stat...
Chang, joy;
Sousa, amina de;
Sabatier, jennifer;
Assane, mariamo;
Zhang, guoqing;
Bila, dulce;
Vaz, paula;
Alfredo, charity;
Cossa, Loide;
Bhatt, Nilesh;
Koumans, emilia, h;
Yang, chunfu;
Rivadeneira, emilia;
Jani, ilesh;
Houston, james, c.
Quantitative plasma viral load (VL) at 1000 copies /mL was recommended as the threshold to confirm antiretroviral therapy (ART) failure by the World Health Organization (WHO). Because of ongoing challenges of using plasma for VL testing in resource-limited settings (RLS), especially for children, this st...
Decroo, Tom;
Telfer, Bárbara;
Dores, Carla Das;
Branco, Ricardo A;
Santos, Natacha Dos;
Mkwamba, Alec;
Dezembro, Sergio;
Joffrisse, Mariano;
Ellman, Tom;
Metcalf , Carol.
Objectives
Estimate the effect of participation in Community ART Groups (CAG) versus individual care on retention-in-care (RIC) on antiretroviral therapy (ART).
Design
Retrospective cohort study.
Setting
High levels of attrition (death or loss-to-follow-up (LTFU) combined) on ART indicate that delivery...
Ndam, Nicaise Tuikue;
Mbuba, Emmanuel;
Gonzalez, Raquel 5;
Cistero, Pau;
Kariuki, Simon;
Sevene, Esperança;
Ruperez, María 5 6;
Fonseca, Ana Maria 5 9;
Vala, Anifa;
Muculuve, Sonia;
Jimenez, Alfons;
Quinto, Llorenç;
Ouma, Peter;
Ramharter, Michael;
Desai, Meghna;
Macete, Eusebio;
Cot, Michel;
Menendez, Clara;
Mayor, Alfredo.
Resistance and tolerance to Plasmodium falciparum can determine the progression of malaria disease. However, quantitative evidence of tolerance is still limited. We investigated variations in the adverse impact of P. falciparum infections among African pregnant women under different intensities of malari...
Gonzalez, Raquel;
Ruperez, , Marı´a;
Sevene, Esperanc¸a;
Vala, Anifa;
Maculuve, So´nia;
Bulo, Helder;
Nhacolo, Arse´nio;
Mayor, Alfredo;
Aponte, John J;
Macete, Euse´bio;
Medenendez, Clara.
The HIV epidemic is concentrated in sub-Saharan Africa. However, limited information exists on its impact on women and infant's health since the introduction of antiretroviral drugs in this region, where health resources are often scarce.
Methods: The effect of HIV infection on maternal health, birth ou...
Fármacos Anti-HIV/uso terapêutico,
Infecções por HIV/terapia,
Infecções por HIV/epidemiologia,
Mortalidade Materna,
Recém-Nascido,
Parto,
d0000680970,
Complicações Infecciosas na Gravidez/terapia,
Complicações Infecciosas na Gravidez/epidemiologia,
Resultado da Gravidez/epidemiologia,
Estudos Prospectivos,
Moçambique
