Total: 1827

Safety of the RTS, S/AS02D candidate malaria vaccine in infants living in a highly endemic area of Mozambique: a double blind randomised controlled phase I/IIb trial

Lancet; 370 (9598), 2007
Background: Malaria remains a leading global health problem that requires the improved use of existing interventions and the accelerated development of new control methods. We aimed to assess the safety, immunogenicity, and initial efficacy of the malaria vaccine RTS,S/AS02D in infants in Africa. Methods...

Epidemiology and clinical presentation of shigellosis in children less than five years of age in rural Mozambique

Pediatr. infect. dis. j; 26 (11), 2007
Rectal swabs were collected from 1354 children <5 years of age with diarrhea attending Manhiça District Hospital and from 227 healthy community controls. Shigellosis incidence was high among children aged 12-47 months (488.4/10(5) child-years at risk). Fever and dysentery were prominent clinical finding...

Varying efficacy of intermittent preventive treatment for malaria in infants in two similar trials: public health implications

Malar. j. (Online); 6 (132), 2007
Background: Intermittent preventive treatment (IPTi) with sulphadoxine-pyrimethamine (SP) in infants resulted in different estimates of clinical malaria protection in two trials that used the same protocol in Ifakara, Tanzania, and Manhiça, Mozambique. Understanding the reasons for the discrepant result...

Prevalence and predictors of maternal peripheral malaria parasitemia in central Mozambique

Am. j. trop. med. hyg; 77 (2), 2007
Malaria infection during pregnancy (MiP) is heterogeneously distributed even in malaria-endemic countries. Program planners require data to facilitate identification of highest-priority populations for MiP control. Using data from two cross-sectional studies of 5,528 pregnant women in 8 neighboring sites...

AAge interactions in the development of naturally acquired immunity to plasmodium falciparum and its clinical presentation

PloS med; 4 (7), 2007
Background Naturally acquired malaria immunity has many determinants and, in the absence of immunological markers of protection, studies assessing malaria incidence through clinical endpoints remain an approach to defining immunity acquisition. We investigated the role of age in disease incidence and th...

Plano estratégico do sector saúde 2007 -2012

Segundo a Organização Mundial da Saúde (OMS), a Saúde é «um estado de completo bem estar físico, mental e social, e não somente ausência de doença ou de enfermidade». 2. A Saúde é um bem precioso que é necessário promover, preservar, manter e melhorar. O Artigo 89 da Constituição da Rep...

Plano estratégico nacional de controlo da tuberculose em Moçambique para o período de 2008 - 2012

Moçambique encontra-se situado na costa do sudeste africano e faz fronteira com a Tanzania a Norte, o Malawi, Zâmbia, Zimbabwe a Este e África do Sul e Swazilândia a Sul. É banhado pelo Oceano Índico a Oeste que se estende ao longo da costa com cerca de 2.470 quilómetros. É uma República, indepe...

Effect of transmission seaseon on the outcome of treatment of urinary schistosomiasis in schoolchildren in matola and maputo, mozambique

The aim of this study was to assess the effect of transmission on the outcome of treatment of urinary schistosomiasis given in two different transmission seasons (high and low) among schoolchildren in the urban and peri-urban areas of Matola and Maputo, southern Mozambique. The results of this study are ...