Resultados: 229

Prevalência da coinfecção HIV e Sífilis em mulheres grávidas em Moçambique

Em 2013, havia no mundo 3,2 milhões de crianças vivendo com HIV, com 91% de infecções ocorrendo em crianças na África subsaariana, através da transmissão de mãe para filho (Transmissão vertical -TV). E sem nenhuma intervenção, o risco de TV varia de 15% a 25% nos países desenvolvidos e de 25...

Reducing mortality in HIV-infected infants and achieving the 90-90-90 target through innovative diagnosis approaches

J. int. aids soc; 18 (6), 2015
Introduction: Despite significant gains in access to early infant diagnosis (EID) over the past decade, most HIV-exposed infants still do not get tested for HIV in the first two months of life. For those who are tested, the long turnaround time between when the sample is drawn and when the results are re...

Post-ART Symptoms Were Not the Problem: A Qualitative Study on Adherence to ART in HIV-Infected Patients in a Mozambican Rural Hospital

PLos ONE; 10 (9), 2015
Objective: The objective of this qualitative study was to explore how clinical symptoms may affect adherence to antiretroviral therapy (ART) in HIV patients, and to explore factors, perceptions and attitudes related to adherence to therapy. Design: A qualitative study was carried out in the context of th...

Implementation and Operational Research: Expedited Results Delivery Systems Using GPRS Technology Significantly Reduce Early Infant Diagnosis Test Turnaround Times

The objective of this study was to quantify the impact of a new technology to communicate the results of an infant HIV diagnostic test on test turnaround time and to quantify the association between late delivery of test results and patient loss to follow-up. We used data collected during a pilot impleme...

Determinants of virological failure and antiretroviral drug resistance in Mozambique

J. antimicrob. chemother; 70 (9), 2015
Objectives: The objective of this study was to inform public health actions to limit first-line ART failure and HIV drug resistance in Mozambique. Methods: This was a cross-sectional study. HIV-1-infected adults on first-line ART for at least 1 year attending routine visits in the Manhiça District Hospi...

Implementation of Point-of-Care Diagnostics Leads to Variable Uptake of Syphilis, Anemia and CD4+ T-Cell Count Testing in Rural Maternal and Child Health Clinics

PLos ONE; 10 (8), 2015
Introduction: Anemia, syphilis and HIV are high burden diseases among pregnant women in sub-Saharan Africa. A quasi-experimental study was conducted in four health facilities in Southern Mozambique to evaluate the effect of point-of-care technologies for hemoglobin quantification, syphilis testing and CD...

Implementation of Point-of-Care Diagnostics Leads to Variable Uptake of Syphilis, Anemia and CD4+ T-Cell Count Testing in Rural Maternal and Child Health Clinics
Implementation of Point-of-Care Diagnostics Leads to Variable Uptake of Syphilis, Anemia and CD4+ T-Cell Count Testing in Rural Maternal and Child Health Clinics

PLos ONE; 10 (8), 2015
A anemia, a sífilis e o VIH são doenças de grande impacto entre as mulheres grávidas na África Subsariana. Foi realizado um estudo quase experimental em quatro unidades de saúde no sul de Moçambique para avaliar o efeito das tecnologias no local de atendimento para quantificação de hemoglobina, ...

Temporal Trends in Patient Characteristics and Outcomes Among Children Enrolled in Mozambique's National Antiretroviral Therapy Program

Pediatr. infect. dis. j; 34 (8), 2015
During 2004-2009, >12,000 children (<15 years old) initiated antiretroviral therapy (ART) in Mozambique. Nationally representative outcomes and temporal trends in outcomes were investigated. Methods: Rates of death, loss to follow-up (LTFU) and attrition (death or LTFU) were evaluated in a nationally re...

Trends in Prevalence of HIV-1 Drug Resistance in a Public Clinic in Maputo, Mozambique

PLos ONE; 10 (7), 2015
Background: An observational study was conducted in Maputo, Mozambique, to investigate trends in prevalence of HIV drug resistance (HIVDR) in antiretroviral (ART) naïve subjects initiating highly active antiretroviral treatment (HAART). Methodology/principal findings: To evaluate the pattern of drug res...

Incidence of HIV and the prevalence of HIV, hepatitis B and syphilis among youths in Maputo, Mozambique: a cohort study

PLos ONE; 10 (3), 2015
Background: Prevalence of HIV in Mozambique among individuals aged 15-49 years is 11.5%. The HIV prevalence is higher in women than in men across the country, peaking at ages 25-29 years and 35-39 years, respectively. In this study, we aimed at determining the prevalence and incidence of HIV, prevalence ...