Resultados: 345

A Balanced Proinflammatory and Regulatory Cytokine Signature in Young African Children Is Associated With Lower Risk of Clinical Malaria

Clin. infect. dis; 69 (Sep.2019), 2019
The effect of timing of exposure to first Plasmodium falciparum infections during early childhood on the induction of innate and adaptive cytokine responses and their contribution to the development of clinical malaria immunity is not well established. As part of a double-blind, randomized, placebo-contr...

Clonal expansion across the seas as seen through CPLP-TB database: A joint effort in cataloguing Mycobacterium tuberculosis genetic diversity in Portuguese-speaking countries

Infect. gent. evol; 72 (), 2019
Tuberculosis (TB) remains a major health problem within the Community of Portuguese Language Speaking Countries (CPLP). Despite the marked variation in TB incidence across its member-states and continued human migratory flux between countries, a considerable gap in the knowledge on the Mycobacterium tube...

Esophageal cancer in Mozambique: should mycotoxins be a concern?

Pan africa Medical Journal; 33 (187), 2019
Fumonisin B1 (FB1) is a mycotoxin frequently found in agricultural commodities. The toxin poses a considerable risk for human and animal health. FB1 is among several mycotoxins produced by Fusarium spp. contaminating virtually any cereal and other Poaceae. Their intracellular action includes the promotio...

Differential patterns of disease and injury in Mozambique: New perspectives from a pragmatic, multicenter, surveillance study of 7809 emergency presentations

PLOS ONE; 14 (7), 2019
There is a paucity of primary data to understand the overall pattern of disease and injuries as well as related health-service utilization in resource-poor countries in Africa. To generate reliable and robust data describing the pattern of emergency presentations attributable to communicable disease (CD)...

Setting the scene and generating evidence for malaria elimination in Southern Mozambique

Malar. j. (Online); 18 (190), 2019
Mozambique has historically been one of the countries with the highest malaria burden in the world. Starting in the 1960s, malaria control efforts were intensified in the southern region of the country, especially in Maputo city and Maputo province, to aid regional initiatives aimed to eliminate malaria ...

Projecting the lives saved by continuing the historical scale-up of child and maternal health interventions in Mozambique until 2030

Background: Over the past 20 years, Mozambique has achieved substantial reductions in maternal, neonatal, and child mortality. However, mortality rates are still high, and to achieve the Sustainable Development Goals (SDGs) for maternal and child health, further gains are needed. One technique that can g...

The incidence of pregnancy hypertension in India, Pakistan, Mozambique, and Nigeria: A prospective population-level analysis

PloS med; 16 (4), 2019
Most pregnancy hypertension estimates in less-developed countries are from cross-sectional hospital surveys and are considered overestimates. We estimated population-based rates by standardised methods in 27 intervention clusters of the Community-Level Interventions for Pre-eclampsia (CLIP) cluster rando...

Prevalência de Parasitoses Intestinais em Crianças nas Escolas Primárias da Província de Sofala, Moçambique

Introdução: O complexo de infecções intestinais parasitárias é causado por organismos que podem ser biologicamente classificados em protozoários ou helmintos. Os parasitas constituem o maior grupo de organismos responsável por infecções em humanos. A província de Sofala localiza-se na regiã...

Self-reported non-receipt of HIV test results: A silent barrier to HIV epidemic control in Mozambique

PLos ONE; 14 (10), 2019
Introduction: People living with HIV (PLHIV) and who are aware of their HIV status can access and benefit from antiretroviral therapy (ART) with subsequent individual and public health benefits; however, many PLHIV are unaware of their HIV status. We assessed the magnitude and determinants of self-report...

Postdischarge Mortality Prediction in Sub-Saharan Africa

Pediatrics; 143 (1), 2019
Background: Although the burden of postdischarge mortality (PDM) in low-income settings appears to be significant, no clear recommendations have been proposed in relation to follow-up care after hospitalization. We aimed to determine the burden of pediatric PDM and develop predictive models to identify c...