There remain challenges in using SARS-CoV-2 RNA diagnostic assays in the respiratory tract
in a pandemic. More so certain countries such as Hong Kong have already included saliva as part of their
mass-testing protocol. The aim of this study was to conduct a systematic review on the alternate use of
saliv...
Anapakala, Elda Muianga;
Anapakala, Elda Muianga;
Chongo, Patrina;
Barca, Isis da;
Dimas, Tomás;
Sitoe, Nadia;
Sebastião, Ruben;
Chongola, Francelino;
Pinto, Isabel;
Loquiha, Osvaldo;
Kidane , Solon;
Jani, Ilesh;
Viegas, Sofia O.
WWDISA is an optional module of the DISA Laboratory Information system (LIS) that offers a web portal that allows access to test results over the internet for patient clinical management. This study aims to assess the applicability of using the WWDISA web application, and the lessons learned from its imp...
Sistemas de Informação,
Laboratórios,
Administração de Serviços de Saúde,
HIV,
Humanos,
Moçambique/epidemiologia,
África,
d0029840,
d0031950,
HIV-1,
Carga Viral
Introduction: The novel coronavirus, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), etiological agent of coronavirus disease 2019 (COVID-19) was first reported in China in December 2019 and spread worldwide. As of March 6th, 2021, there have been 116,670,105 million confirmed cases globall...
África/epidemiologia,
COVID-19/epidemiologia,
Doenças Transmissíveis Importadas,
Anticoncepção,
Saúde Global,
Humanos,
Moçambique/epidemiologia,
Adolescente,
Pandemias,
Gravidade do Paciente,
SARS-CoV-2,
Doenças Transmissíveis Importadas/epidemiologia
As survival among people living with HIV (PLHIV) improves with universal HIV treatment, new strategies are needed to support management of co-morbidities like type 2 diabetes (T2D). We assessed prediabetes and T2D prevalence and risk factors using haemoglobin A1c (HbA1c) among PLHIV on antiretroviral the...
Diabetes Mellitus Tipo 2/complicações,
Diabetes Mellitus Tipo 2/tratamento farmacológico,
Estado Pré-Diabético,
Hemoglobinas Glicadas,
Glicemia,
Humanos,
Quênia/epidemiologia,
Infecções por HIV/complicações,
Infecções por HIV/tratamento farmacológico,
Infecções por HIV/epidemiologia,
Estado Pré-Diabético/epidemiologia,
Estado Pré-Diabético/diagnóstico
Matsuzaki, Mika;
Sherr, Kenneth;
Augusto, Orvalho;
Kawakatsu, Yoshito;
Ásbjörnsdóttir, Kristjana;
Chale, Falume;
Covele, Alfredo;
Manaca, Nélia;
Muanido, Alberto;
Wagenaan, Bradley H;
Mocumbi, Ana O;
Gimbel, Sarah.
Hypertension (HTN) is a major risk factor for cardiovascular diseases, and its prevalence has been rising in low- and middle-income countries. The current study describes HTN prevalence in central Mozambique, association between wealth and blood pressure (BP), and HTN monitoring and diagnosis practice am...
Fernandez, Sheila;
Augusto, Orvalho;
Fuente-Soro, Laura;
Menéndez, Clara;
López-Varela, Elisa;
Naniche, Denise;
Bernardo, Edson;
Nhampossa, Tacilta;
Maculuve, Sónia;
Casellas, Aina;
Ruperez, Maria.
It is often assumed that children and their caregivers either stay in care together or discontinue together, but data is lacking on caregiver–child retention concordance. We sought to describe the pattern of care among a cohort of human immunodeficiency virus (HIV) infected children and mothers enrolle...
Inguane, Celso;
Sawadogo-Lewis, Talata;
Chaquisse, Eusébio;
Roberton, Timothy;
Ngale, Kátia;
Fernandes, Quinhas;
Dinis, Aneth;
Orvalho, Augusto;
Covele, Alfredo;
Hicks, Leecreesha;
Gremu, Artur;
Sherr, Kenneth.
The need for evidence-based decision-making in the health sector is well understood in the global health community. Yet, gaps persist between the availability of evidence and the use of that evidence. Most research on evidence-based decision-making has been carried out in higher-income countries, and mos...
Background: Malaria is one of the most widespread and deadly diseases worldwide and large majority of malaria cases and deaths occurs in Africa. Efforts to develop an effective vaccine against malaria are underway and several vaccine prototypes are on different clinical trial phases.Objective: As many su...
Lamp, Katherine;
McGovern , Seth;
Fong, Youyi;
Atem, Charles Diko;
Nfetam, Jean Bosco Elat;
Nzuobontane 3, Divine;
Bollinger, Timothy;
Jani 6, Ilesh;
Sitoe, Nadia;
Kiyaga 7, Charles;
Senyama, George;
Mangwendeza, Phibeon M;
Zinyowera, Sekesai Mtapuri;
Doi, Naoko;
Peter, Trevor;
Sacks, Jilian A;
Vojnov, Lara.
Background: Globally, nearly 22 million HIV-infected patients are currently accessing antiretroviral treatment; however, almost one million people living with HIV died of AIDS-related illnesses in 2018. Advanced HIV disease remains a significant issue to curb HIV-related mortality.
Methods: We analyzed 8...
Uganda,
Atenção Primária à Saúde,
Humanos,
Infecções por HIV,
Coleta de Dados,
Camarões,
Contagem de Linfócito CD4,
Instituições de Assistência Ambulatorial,
África Subsaariana/epidemiologia,
Epidemiologia,
Moçambique/epidemiologia
Viegas, Edna O;
Arne, Kroidl;
Munseri, Patricia J;
Missanga, Marco;
Nilsson, Charlotta;
Tembe, Nelson;
Bauer, Asli;
Joachin, Agricola;
Joseph, Sarah;
Mann, Philipp;
Geldmacher, Christof;
Fleck, Sue;
Stöhr, Wolfgang;
Scarlatti, Gabriella;
Aboud, Said;
Bakari, Muhammad;
Maboko, Leonard;
Hoelscher, Michael;
Wahren, Britta;
Robb, Merlin L;
Weber, Jonathan;
McCormack, Sheena;
Biberfeld, Gunnel;
Jani, Ilesh V;
Sandström, Eric;
Lyamuya, Eligius.
Background: We evaluated the safety and immunogenicity of (i) an intradermal HIV-DNA regimen given with/without intradermal electroporation (EP) as prime and (ii) the impact of boosting with modified vaccinia virus Ankara (HIV-MVA) administered with or without subtype C CN54rgp140 envelope protein adjuva...
Adulto Jovem,
Vacinas Virais,
Alergia e Imunologia,
Genética,
Vacinas de DNA,
Vacinação,
Tanzânia/epidemiologia,
Moçambique/epidemiologia,
Humanos,
Voluntários Saudáveis,
Eletroporação,
Anticorpos Neutralizantes,
Adulto,
Administração Cutânea,
Vacinas contra a AIDS
