Floridia, Marco;
Ciccacci, Fausto;
Andreotti, Mauro;
Hassane, Archa;
Sidumo, Zita;
Magid, Nurja A;
Sotomane, Horacio;
David, Muhlavasse;
Mutemba, Elsa;
Cebola, Junia;
Mugunhe, Remigio José;
Riccardi, Fabio;
Marazzi, Maria Cristina;
Giuliano, Marina;
Palombi, Leonardo;
Mancinelli, Sandro.
Tuberculosis is a major health concern in several countries, and effective diagnostic algorithms for use in human
immunodeficiency virus (HIV)–positive patients are urgently needed.
Methods. At prescription of antiretroviral therapy, all patients in 3 Mozambican health centers were screened for tubercu...
Algoritmos,
Terapia Antirretroviral de Alta Atividade,
Antituberculosos,
Infecções por HIV/tratamento farmacológico,
Lipopolissacarídeos,
Técnicas de Diagnóstico Molecular,
Moçambique,
Mycobacterium tuberculosis,
Prevalência,
Sensibilidade e Especificidade,
Tuberculose Pulmonar/diagnóstico,
Escarro
Background: Genotypic molecular testing may be very helpful for tuberculosis (TB) drug-resistance surveillance and for treatment guidance in low resource settings.
Methods: Descriptive analysis of M. tuberculosis isolates from Beira Central Hospital, Mozambique, during 2014-2015. Genotype MTBDRplus and ...
Vários fatores ambientais e do hospedeiro contribuem para o desfecho da tuberculose, curiosamente polimorfismos de nucleotídeo único (SNPs) em genes candidatos têm sido avaliados em populações com diferentes etnias e infecção por TB. No presente estudo, focamos em SNPs em citocinas e genes mediad...
As complicações respiratórias são mais comuns na Unidade de Cuidados Intensivos que ocasionalmente, levam ao risco à vida do paciente. A pneumonia hospitalar é uma das complicações respiratórias mais frequente na unidade de cuidados intensivos, colocando o paciente num estado de sofrimento e aum...
Introduction: Chest radiography remains a critical tool for diagnosing intrathoracic tuberculosis (TB) in young children who are unable to expectorate. We describe the radiological findings in children under 3 years of age investigated for TB in the district of Manhiça, southern Mozambique, an area with...
We used data from a randomized trial of HIV-tuberculosis co-infected patients in Mozambique to determine the incidence and predictors of paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome (IRIS) occurring within 12 weeks of starting antiretroviral therapy, and to evaluate its...
In countries with a high incidence of HIV and tuberculosis co-infection, nevirapine and efavirenz are widely used as antiretroviral therapy but both interact with antituberculosis drugs. We aimed to compare efficacy and safety of a nevirapine-based antiretroviral therapy (started at full dose) with an ef...
Infecções Oportunistas Relacionadas com a AIDS/terapia,
Fármacos Anti-HIV/administração & dosagem,
Fármacos Anti-HIV/uso terapêutico,
Fármacos Anti-HIV/efeitos da radiação,
Antituberculosos/uso terapêutico,
Benzoxazinas/uso terapêutico,
Benzoxazinas/administração & dosagem,
Benzoxazinas/efeitos adversos,
Coinfecção,
Ciclopropanos,
Interações Medicamentosas,
Quimioterapia Combinada,
Infecções por HIV/terapia,
Nevirapina/uso terapêutico,
Nevirapina/efeitos adversos,
Nevirapina/administração & dosagem,
Resultado do Tratamento,
Tuberculose/complicações,
Tuberculose/terapia,
Tuberculose Pulmonar/complicações,
Tuberculose Pulmonar/terapia,
Moçambique/epidemiologia
Viegas, sofia omar;
Machado, adelina;
Groenheit, Ramona;
Ghebremichael, solomon;
Pennhag, alexandra;
Gudo, eduardo samo;
Cuna, zaina;
Langa, egídio;
Miotto, paolo;
Cirillo, Daniela, M.
The Beijing genotype is a lineage of Mycobacterium tuberculosis that is distributed worldwide and responsible for large epidemics, associated with multidrug-resistance. However, its distribution in Africa is less understood due to the lack of data. Our aim was to investigate the prevalence and possible t...
Tuberculosis (TB) presents a serious problem in Mozambique. HIV prevalence among TB patients is estimated at 47%. A delay in having their first CD4+ cell count could lead to a missed opportunity for ART initiation due to a CD4+ cell increase above the cut-off caused by TB treatment. The objective is to d...
Viegas, sofia omar;
Machado, adelina;
Groenheit, Ramona;
Ghebremichael, solomon;
Pennhag, alexandra;
Gudo, paula, s;
Cuna, zaina;
Langa, egídio;
Miotto, paolo;
Cirillo, Daniela, M.
Background: Mozambique is one of the countries with the highest burden of tuberculosis (TB) in Sub-Saharan Africa, and information on the predominant genotypes of Mycobacterium tuberculosis circulating in the country are important to better understand the epidemic. This study determined the predominant s...
