Resultados: 26

Efficacy of sulphadoxine-pyrimethamine with or without artesunate for the treatment of uncomplicated Plasmodium falciparum malaria in southern Mozambique: a randomized controlled trial

Malar. j. (Online); 8 (141), 2009
Background: An artemisinin-based combination therapy, artesunate (AS) plus sulphadoxine-pyrimethamine (SP), was compared to SP monotherapy to provide evidence of further treatment options in southern Mozambique. Methods: Between 2003 and 2005, 411 patients over one year and 10 kg with uncomplicated Plasm...

Cost-effectiveness of malaria intermittent preventive treatment in infants (IPTi) in Mozambique and the United Republic of Tanzania

Bull. W.H.O. (Online); 87 (2), 2009
Objective: To estimate the cost-effectiveness of malaria intermittent preventive treatment in infants (IPTi) using sulfadoxine-pyrimethamine (SP). Methods: In two previous IPTi trials in Ifakara (United Republic of Tanzania) and Manhiça (Mozambique), SP was administered three times to infants before 9 m...

Impact of intermittent preventive treatment with sulfadoxine-pyrimethamine on antibody responses to erythrocytic-stage Plasmodium falciparum antigens in infants in Mozambique

Clin. vaccine immunol; 15 (8), 2008
We evaluated the impact of intermittent preventive treatment in infants (IPTi) with sulfadoxine-pyrimethamine (SP), which was given at ages 3, 4, and 9 months through the Expanded Program on Immunization (EPI), on the development of antibody responses to Plasmodium falciparum in Mozambique. Immunoglobuli...

Seven years of regional malaria control collaboration--Mozambique, South Africa, and Swaziland

Am. j. trop. med. hyg; 76 (1), 2007

The influence of maloprim chemoprophylaxis on cellular and humoral immune responses to plasmodium falciparum asexual blood stage antigens in schoolchildren living in a malaria endemic area of Mozambique

Acta trop.; 57 (4), 1994
We examined the impact of chemoprophylaxis on the cellular and humoral immune responses to polypeptides of the asexual Plasmodium falciparum blood stage antigens, the glutamate rich protein GLURP and Pf155/RESA, both of which in previous field studies have been identified as potentially protective antige...

Evaluation of four therapeutic regimens for falciparum malaria in Mozambique, 1986

Bull. W.H.O. (Online); 66 (2), 1988
A randomized study on the effect of the following four treatment regimens on Plasmodium falciparum parasitaemia was carried out on 200 asymptomatic schoolchildren in Maputo, Mozambique: chloroquine (25 mg/kg body weight), amodiaquine (25 mg/kg), sulfadoxine-pyrimethamine (25 mg/kg and 1.25 mg/kg), or amo...