Izco, Santiago;
Murias-Closas, Adrià;
Jordan, Alexander M;
Greene, Gregory;
Catorze, Nteruma;
Chiconela, Helio;
Garcia, Juan Ignacio;
Blanco-Arevalo, Alejandro;
Febrer, Anna;
Casellas, Aina;
Saavedra, Belén;
Chiller, Tom;
Nhampossa, Tacilta;
Garcia-Basteiro, Alberto;
Letang, Emilio.
Introduction: AIDS-mortality remains unacceptably high in sub-Saharan Africa, largely driven by advanced HIV disease (AHD). We nested a study in an existing tuberculosis (TB) contact-tracing intervention (Xpatial-TB). The aim was to assess the burden of AHD among high-risk people living with HIV (PLHIV) ...
Kenga, Darlenne B;
Gebretsadik, Tebeb;
Simbine, Samuel;
Simbine, Samuel;
Maússe, Fabião E;
Charles, Pedro;
Zaqueu, Ernesto;
Fernando, Hermenegilda F;
Sacarlal, Jahit;
Moon, Troy D.
Background: Bacteremia is a major cause of morbidity and mortality worldwide. Children infected with HIV present with patterns of bacteremia generally associated with poor prognosis. In Mozambique, data on bacteremia are sparce.
Methods: We conducted an observational study of HIV-infected and HIV-expose...
Antibacterianos/uso terapêutico,
Bacteriemia/epidemiologia,
Bacteriemia/tratamento farmacológico,
Infecções Comunitárias Adquiridas/tratamento farmacológico,
Infecções Comunitárias Adquiridas/epidemiologia,
Febre/tratamento farmacológico,
Infecções por HIV/epidemiologia,
Infecções por HIV/complicações,
Infecções por HIV/tratamento farmacológico,
Testes de Sensibilidade Microbiana,
Infecções Estafilocócicas/tratamento farmacológico,
Moçambique/epidemiologia
Mayor, Alfredo;
Silva, Clemente;
Valbona, Eduard Rovira;
Feltrer, Arantxa Roca;
Bonnington, Craig;
Smith, Alexandra Wharton;
Greehouse, Bryan;
Bever, Caitlin;
Chidimatembue, Arlindo;
Guinovart, Caterina;
Proctor, Joshua L;
Rodrigues, Maria;
Canana, Neide;
Arnaldo, Paulo;
Boene, Simone;
Enosse, Sonia;
Saute, Francisco;
Candrinho, Baltazar.
Introduction: Genomic data constitute a valuable adjunct to routine surveillance that can guide programmatic decisions to reduce the burden of infectious diseases. However, genomic capacities remain low in Africa. This study aims to operationalise a functional malaria molecular surveillance system in Moz...
Sevene, Esperança;
Boene, Helena;
Vidler, Marianne;
Valá, Anifa;
Macuacua, Salésio;
Augusto, Orvalho;
Fernandes, Quinhas;
Macete, Eusébio;
Sidat, Mohsin;
Dadelszen, Peter von;
Munguambe, Khátia;
Bique, Cassimo.
Background
Maternal mortality is an important public health problem in low-income countries. Delays in reaching health facilities and insufficient health care professionals call for innovative community-level solutions. There is limited evidence on the role of community health workers in the management o...
Competência Clínica,
Serviços de Saúde Comunitária/normas,
Agentes Comunitários de Saúde/psicologia,
Gerenciamento Clínico,
Tratamento de Emergência/normas,
Estudos de Viabilidade,
Conhecimentos, Atitudes e Prática em Saúde,
Mortalidade Materna,
Aceitação pelo Paciente de Cuidados de Saúde,
Pré-Eclâmpsia/diagnóstico,
Pré-Eclâmpsia/terapia,
Cuidado Pré-Natal,
Encaminhamento e Consulta,
Moçambique
Soler, Helena Marti;
Máquina, Mara;
Opiyo, Mercy;
Alafo, Celso;
Smith, Ellie Sherrard;
Malheia, Arlindo;
Cuamba 6, Nelson;
Sacoor, Charfudin;
Rabinovich, Niquice;
Aide, Pedro;
Saúte, Francisco;
Paaijmans, Krijn.
Indoor residual spraying (IRS) is one of the main malaria vector control strategies in Mozambique alongside the distribution of insecticide treated nets. As part of the national insecticide resistance management strategy, Mozambique introduced SumiShield™ 50WG, a third generation IRS product, in 2018. ...
Interrupted time-series (ITS) designs are a robust and increasingly popular nonrandomized study design for strong causal inference in the evaluation of public health interventions. One of the most common techniques for model parameterization in the analysis of ITS designs is segmented regression, which u...
Altered mental status (AMS) is a priority presenting sign that must be assessed in HIV-infected, febrile children, yet diagnosis is difficult in areas with limited diagnostic capacity. Malaria and bacterial meningitis have been reported as the most common causes of AMS in febrile children presenting to t...
Ongaro, Linda;
Mondal, Mayukh;
Flores, Rodrigo;
Marnetto, Davide;
Molinaro, Ludovica;
Alarcón-Riquelme, Marta;
Moreno-Estrada, Andrés;
Mabunda, Nedio;
Ventura, Mario;
Tambets, Kristiina;
Hellenthal, Garrett;
Capelli, Cristian;
Kivisild, Toomas;
Metspalu, Mait;
Pagani, Luca;
Montinaro, Francesco.
American populations are one of the most interesting examples of recently admixed groups, where ancestral components from three major continental human groups (Africans, Eurasians and Native Americans) have admixed within the last 15 generations. Recently, several genetic surveys focusing on thousands of...
A monitoria da Carga Viral (CV) em pacientes em Tratamento Antirretroviral (TARV) é importante para avaliar o sucesso do tratamento. Em Moçambique, o teste de CV é recomendado para todos os pacientes em TARV, 6 meses após o início do TARV, e de forma rotineira a cada 12 meses se a CV for <1000 cópi...
Advancements in global mental health implementation research have revealed promising strategies for improving access to evidence-based mental health care. These advancements have not translated, however, into a reduced prevalence of mental disorders. In this review we examine the relationships between de...
