Resultados: 338

Rapid increase of Plasmodium falciparum dhfr/dhps resistant haplotypes, after the adoption of sulphadoxine-pyrimethamine as first line treatment in 2002, in southern Mozambique

Malar. j. (Online); 7 (115), 2008
In late 2002, the health authorities of Mozambique implemented sulphadoxine-pyrimethamine (SP)/amodiaquine (AQ) as first-line treatment against uncomplicated falciparum malaria. In 2004, this has been altered to SP/artesunate in line with WHO recommendations of using Artemisinin Combination Therapies (AC...

Malaria in rural Mozambique. Part II: children admitted to hospital

Malar. j. (Online); 7 (37), 2008
Background: Characterization of severe malaria cases on arrival to hospital may lead to early recognition and improved management. Minimum community based-incidence rates (MCBIRs) complement hospital data, describing the malaria burden in the community. Methods: A retrospective analysis of all admitted m...

Malaria in rural Mozambique. Part I: children attending the outpatient clinic

Malar. j. (Online); 7 (36), 2008
Background: Malaria represents a huge burden for the health care services across Africa. Describing malaria attending health services contributes to quantify the burden and describe the epidemiology and clinical presentation. Methods: Retrospective analysis of data collected through the Manhiça morbidit...

Tríade álcool, acidente e trauma: Estudo em motoristas na Província e Cidade de Maputo

Os traumas resultantes dos acidentes de viação são reconhecidos mundialmente como um problema importante de saúde pública, atingindo milhares de pessoas de vários estratos sócio-económicos sem distinção de género ou grupo etário. Em Moçambique, como em muitos países em desenvolvimento, os t...

Contribuição para o estudo de resistência aos antimaláricos e análise de marcadores moleculares de Plasmodium falciparum e do hospedeiro humano, em Maputo, Moçambique
Contribution to the study of antimalarial resistance and analysis of molecular markers of Plasmodium falciparum and the human host, in Maputo, Mozambique

A malária é de longe a doença parasitária mais importante em Moçambique, constituindo um grave problema de saúde pública no País. Apesar de se considerar que um diagnóstico atempado e um tratamento correcto são os elementos básicos para um programa de controlo da malária bem sucedido, nas úl...

Safety of the RTS, S/AS02A malaria vaccine in Mozambican children during a Phase IIb trial
Safety of the RTS,S/AS02A malaria vaccine in Mozambican children during a Phase IIb trial

Vaccine; 26 (2), 2008
RTS,S/AS02A is a pre-erythrocytic vaccine candidate based on the Plasmodium falciparum circumsporozoite surface antigen and is currently the most advanced malaria vaccine candidate in development. A proof of concept phase IIb trial of the RTS,S/AS02A in Mozambican children aged 1-4 years determined a vac...

Epidemiology and clinical presentation of shigellosis in children less than five years of age in rural Mozambique

Pediatr. infect. dis. j; 26 (11), 2007
Rectal swabs were collected from 1354 children <5 years of age with diarrhea attending Manhiça District Hospital and from 227 healthy community controls. Shigellosis incidence was high among children aged 12-47 months (488.4/10(5) child-years at risk). Fever and dysentery were prominent clinical finding...

Safety and immunogenicity of the RTS, S/AS02A candidate malaria vaccine in children aged 1–4 in Mozambique

Trop. med. int. health; 29 (1), 2007
The development of a malaria vaccine remains a public health priority for sub-Saharan Africa. RTS,S/AS02A candidate malaria vaccine has been shown to be safe and immunogenic in previous studies in adults and staggered dose-escalation studies in children in The Gambia. However, genetic features and the in...

Seven years of regional malaria control collaboration--Mozambique, South Africa, and Swaziland

Am. j. trop. med. hyg; 76 (1), 2007

“A epidemia pelo HIV/AIDS e suas repercussões sobre a saúde da população moçambicana (1986 a 2003)”
The hiv/aids epidemic and its repercussions on the health of the mozambican population (1986 to 2003)

Em 1997, data do último censo, a população moçambicana era em número de 16.099.246 habitantes. Segundo as estimativas do Instituto Nacional de Estatística em Moçambique (INE) referente a 2005, a população moçambicana é de 19.420.036 habitantes. Moçambique situa-se na faixa sul-oriental do Con...