Objectives: We describe nevirapine and efavirenz exposure on and off tuberculosis treatment and consequences for virological efficacy and tolerance in patients included in the ANRS 12146/12214-CARINEMO trial.
Methods: Participants were randomly selected to receive either nevirapine at 200 mg twice daily...
Alcinos,
Terapia Antirretroviral de Alta Atividade/métodos,
Antituberculosos/uso terapêutico,
Benzoxazinas/uso terapêutico,
Ciclopropanos,
Infecções por HIV/terapia,
Tolerância a Medicamentos,
Fármacos Anti-HIV/uso terapêutico,
Infecções/complicações,
Nevirapina/uso terapêutico,
Tuberculose/terapia,
Tuberculose/complicações,
Resultado do Tratamento,
Moçambique
Objective To generate maps reflecting the intersection of community-based Voluntary Counseling and Testing (VCT) delivery points with facility-based HIV program demographic information collected at the district level in three districts (Ile, Maganja da Costa and Chinde) of Zambézia Province, Mozambique;...
Elul, batya;
Lahuerta, maria;
Abacassamo, Fatima;
Lamb, matthew, r;
Ahoua, laurence;
McNairy, margaret, l;
Tomo, Maria;
Horowitz, deborah;
Sutton, roberta;
Mussa, antonio;
Gurr, danielle;
Jani, ilesh, v.
Background: Despite the extraordinary scale up of HIV prevention, care and treatment services in sub-Saharan Africa (SSA) over the past decade, the overall effectiveness of HIV programs has been significantly hindered by high levels of attrition across the HIV care continuum. Data from “real-life” se...
Ao longo de algumas décadas, a epidemia do HIV e SIDA tornou-se num ícone de grandes questões que afligem o mundo devido a sua dinâmica que configura suas manifestações de acordo com as características culturais e sócio demográficas em diferentes populações. O HIV e SIDA constitui um dos grand...
In countries with a high incidence of HIV and tuberculosis co-infection, nevirapine and efavirenz are widely used as antiretroviral therapy but both interact with antituberculosis drugs. We aimed to compare efficacy and safety of a nevirapine-based antiretroviral therapy (started at full dose) with an ef...
Infecções Oportunistas Relacionadas com a AIDS/terapia,
Fármacos Anti-HIV/administração & dosagem,
Fármacos Anti-HIV/uso terapêutico,
Fármacos Anti-HIV/efeitos da radiação,
Antituberculosos/uso terapêutico,
Benzoxazinas/uso terapêutico,
Benzoxazinas/administração & dosagem,
Benzoxazinas/efeitos adversos,
Coinfecção,
Ciclopropanos,
Interações Medicamentosas,
Quimioterapia Combinada,
Infecções por HIV/terapia,
Nevirapina/uso terapêutico,
Nevirapina/efeitos adversos,
Nevirapina/administração & dosagem,
Resultado do Tratamento,
Tuberculose/complicações,
Tuberculose/terapia,
Tuberculose Pulmonar/complicações,
Tuberculose Pulmonar/terapia,
Moçambique/epidemiologia
Stigma has been implicated in poor outcomes of human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) care. Reducing stigma is important for HIV prevention and long-term treatment success. Although stigma reduction interventions are conducted in Mozambique, little is known about the...
Síndrome da Imunodeficiência Adquirida/epidemiologia,
Síndrome da Imunodeficiência Adquirida/psicologia,
Fármacos Anti-HIV/uso terapêutico,
Consenso,
Soropositividade para HIV/psicologia,
Soropositividade para HIV/epidemiologia,
Estigma Social,
Necessidades e Demandas de Serviços de Saúde,
Conhecimentos, Atitudes e Prática em Saúde,
Pessoal de Saúde,
Moçambique/epidemiologia
Background: The prevalence of hepatitis B virus (HBV) infection and human immunodeficiency virus (HIV) infection in Mozambique is one of the highest in the world, though in spite of this the prevalence of occult hepatitis B infection (OBI) is unknown.
Objectives: This study was conducted with the aim to ...
Bergeron, michèle;
Daneau, géraldine;
Ding, tao;
Sitoe, Nádia;
Westerman, larry, e;
Stokx, jocelijn;
Jani, ilesh, v;
Coetzee, lindi, m;
Scott, lesley;
Weggheleire, anja de;
Boel, Luc;
Stevens, wendy, s;
Glencross, deborah;
Peter, trevor, f.
Introduction: Point-of-care (POC) CD4 testing can improve access to treatment by enabling decentralization and reducing patient loss-to-follow-up. As new POC CD4 technologies become available, their performance should be assessed before widespread deployment. This study reports the findings of five indep...
Saracino, Annalisa;
Nacarapa, Edy A;
da Costa Massinga, Ézio A;
Martinelli, Domenico;
Martinelli, Domenico;
Scacchetti, Marco;
de Oliveira, Carlos;
Antonich, Anita;
Galloni, Donata;
Ferro, Josefo J;
Macome, César A.
Mozambique presents a very high prevalence of both malaria and HIV infection, but the impact of co-cancel infection on morbidity in this population has been rarely investigated. The aim of this study was to describe the prevalence and clinical characteristics of malaria in hospitalized adult HIV-positive...
Lambdin, Barrot H;
Micek, Mark A;
Koepsell, Thomas D;
Hughes, James P;
Sherr, Kenneth;
Pfeiffer, James;
Karagianis, Marina;
Lara, Joseph;
Gloyd, Stephen S;
Stergachis, Andy.
Since the rapid scale-up of antiretroviral therapy (ART) programs in sub-Saharan Africa, electronic patient tracking systems (EPTS) have been deployed to respond to the growing demand for program monitoring, evaluation and reporting to governments and donors. These routinely collected data are often used...
