Resultados: 438

Assessment of measles immunity among infants in Maputo City, Mozambique

Background: The optimum age for measles vaccination varies from country to country and thus a standardized vaccination schedule is controversial. While the increase in measles vaccination coverage has produced significant changes in the epidemiology of infection, vaccination schedules have not been adjus...

Rapid increase of Plasmodium falciparum dhfr/dhps resistant haplotypes, after the adoption of sulphadoxine-pyrimethamine as first line treatment in 2002, in southern Mozambique

Malar. j. (Online); 7 (115), 2008
In late 2002, the health authorities of Mozambique implemented sulphadoxine-pyrimethamine (SP)/amodiaquine (AQ) as first-line treatment against uncomplicated falciparum malaria. In 2004, this has been altered to SP/artesunate in line with WHO recommendations of using Artemisinin Combination Therapies (AC...

Molecular Markers of Resistance to Sulfadoxine-Pyrimethamine during Intermittent Preventive Treatment for Malaria in Mozambican Infants

J. infect. dis; 197 (12), 2008
Background. Intermittent preventive treatment in infants (IPTi) with sulfadoxine-pyrimethamine (SP) is a po tential malaria control strategy. There is concern about the impact that increasing in vivo resistance to SP has on the efficacy of IPTi, as well as about the potential contribution of IPTi to incr...

Malaria in rural Mozambique. Part II: children admitted to hospital

Malar. j. (Online); 7 (37), 2008
Background: Characterization of severe malaria cases on arrival to hospital may lead to early recognition and improved management. Minimum community based-incidence rates (MCBIRs) complement hospital data, describing the malaria burden in the community. Methods: A retrospective analysis of all admitted m...

Malaria in rural Mozambique. Part I: children attending the outpatient clinic

Malar. j. (Online); 7 (36), 2008
Background: Malaria represents a huge burden for the health care services across Africa. Describing malaria attending health services contributes to quantify the burden and describe the epidemiology and clinical presentation. Methods: Retrospective analysis of data collected through the Manhiça morbidit...

Tríade álcool, acidente e trauma: Estudo em motoristas na Província e Cidade de Maputo

Os traumas resultantes dos acidentes de viação são reconhecidos mundialmente como um problema importante de saúde pública, atingindo milhares de pessoas de vários estratos sócio-económicos sem distinção de género ou grupo etário. Em Moçambique, como em muitos países em desenvolvimento, os t...

Contribuição para o estudo de resistência aos antimaláricos e análise de marcadores moleculares de Plasmodium falciparum e do hospedeiro humano, em Maputo, Moçambique
Contribution to the study of antimalarial resistance and analysis of molecular markers of Plasmodium falciparum and the human host, in Maputo, Mozambique

A malária é de longe a doença parasitária mais importante em Moçambique, constituindo um grave problema de saúde pública no País. Apesar de se considerar que um diagnóstico atempado e um tratamento correcto são os elementos básicos para um programa de controlo da malária bem sucedido, nas úl...

Safety of the RTS, S/AS02A malaria vaccine in Mozambican children during a Phase IIb trial
Safety of the RTS,S/AS02A malaria vaccine in Mozambican children during a Phase IIb trial

Vaccine; 26 (2), 2008
RTS,S/AS02A is a pre-erythrocytic vaccine candidate based on the Plasmodium falciparum circumsporozoite surface antigen and is currently the most advanced malaria vaccine candidate in development. A proof of concept phase IIb trial of the RTS,S/AS02A in Mozambican children aged 1-4 years determined a vac...

Epidemiology and clinical presentation of shigellosis in children less than five years of age in rural Mozambique

Pediatr. infect. dis. j; 26 (11), 2007
Rectal swabs were collected from 1354 children <5 years of age with diarrhea attending Manhiça District Hospital and from 227 healthy community controls. Shigellosis incidence was high among children aged 12-47 months (488.4/10(5) child-years at risk). Fever and dysentery were prominent clinical finding...

Prevalence of rheumatic heart disease detected by echocardiographic screening

N. Engl. j. med; 357 (5), 2007
Background: Epidemiologic studies of the prevalence of rheumatic heart disease have used clinical screening with echocardiographic confirmation of suspected cases. We hypothesized that echocardiographic screening of all surveyed children would show a significantly higher prevalence of rheumatic heart dis...