Total: 1827

Limitations to current methods to estimate cause of death: a validation study of a verbal autopsy model

Gates Open Res; 16 (1), 2020
Background: Accurate information on causes of death (CoD) is essential to estimate burden of disease, track global progress, prioritize cost-effective interventions, and inform policies to reduce mortality. In low-income settings, where a significant proportion of deaths take place at home or in poorly-r...

Loss to follow-up and opportunities for reengagement in HIV care in rural Mozambique. A prospective cohort study

Medicine journal; 99 (6), 2020
Patients lost to follow-up (LTFU) over the human immunodeficiency virus (HIV) cascade have poor clinical outcomes and contribute to onward HIV transmission. We assessed true care outcomes and factors associated with successful reengagement in patients LTFU in southern Mozambique. Newly diagnosed HIV-posi...

Pulmonary tuberculosis (PTB) is frequently associated with chronic respiratory impairment despite microbiological cure. There are only a few clinical research studies that describe the course, type and severity as well as associated risk factors for lung impairment (LI) in TB patients

Pulmonary tuberculosis (PTB) is frequently associated with chronic respiratory impairment despite microbiological cure. There are only a few clinical research studies that describe the course, type and severity as well as associated risk factors for lung impairment (LI) in TB patients....

Demographic and health community-based surveys to inform a malaria elimination project in magude district, southern Mozambique

BMJ Open; 10 (5), 2020
Objectives: A Demographic and Health Platform was established in Magude in 2015, prior to the deployment of a project aiming to evaluate the feasibility of malaria elimination in southern Mozambique, named the Magude project. This platform aimed to inform the design, implementation and evaluation of the ...

Determining hematological, biochemical and immunological reference values in healthy adults with high-risk for HIV acquisition in Mozambique

n many African countries, laboratory reference values are not established for the local healthy adult population. In Mozambique, reference values are known for young adults (18- 24yo) but not yet established for a wider age range. Our study aimed to establish hematological, biochemical and immunological ...

Tuberculosis bacillary load, an early marker of disease severity: the utility of tuberculosis Molecular Bacterial Load Assay

Thorax; 75 (7), 2020
In this comparative biomarker study, we analysed 1768 serial sputum samples from 178 patients at 4 sites in Southeast Africa. We show that tuberculosis Molecular Bacterial Load Assay (TB-MBLA) reduces time-to-TB-bacillary-load-result from days/weeks by culture to hours and detects early patient treatment...

Intestinal protozoan infections among children 0-168 months with diarrhea in Mozambique: June 2014 - January 2018

Plos negl. trop. dis; 14 (4), 2020
Intestinal parasites such as Cryptosporidium spp., Giardia lamblia and Entamoeba histolytica can cause severe diarrhea, especially among children in developing countries. This study aims to determine the frequency of Cryptosporidium spp., Giardia lamblia and Entamoeba histolytica in children with diarrhe...

HIV prevalence and TB in migrant miners communities of origin in Gaza Province, Mozambique: the need for increasing awareness and knowledge

PLos ONE; 15 (4), 2020
As part of ongoing efforts to generate evidence needed on HIV and tuberculosis (TB) to inform policies and programs aimed to improve the health outcomes of migrants and communities affected by migration and mining, a preliminary investigation was conducted through a biological and behavioral (BBS) approa...

First trimester use of artemisinin-based combination therapy and the risk of low birth weight and small for gestational age

Malar. j. (Online); 19 (1), 2020
While there is increasing evidence on the safety of artemisinin-based combination therapy (ACT) for the case management of malaria in early pregnancy, little is known about the association between exposure to ACT during the first trimester and the effect on fetal growth. Data were analysed from prospecti...

Manual de prevenção de COVID-19

Após descoberta da infecção respiratória aguda causada pelo Sars-Cov-2 na província de Wuhan na China em Dezembro de 2019, a OMS declarou a 30 de Janeiro de 2020 a COVID-19 como sendo a 6ª emergência mundial de saúde pública a seguir a pandemias de H1N1 (2009), Pólio (2014), Ébola no Oeste de ...