Total: 1827

Relatório da Ronda Nacional da Avaliação Externa da Qualidade de Dados (AeQD) 2017

Este relatório apresenta os resultados da IV Ronda Nacional de Avaliação Externa da Qualidade de Dados (AeQD), realizada entre Março e Setembro de 2017. A Avaliação Externa de Qualidade de Dados foi liderada pelo Ministério da Saúde (MISAU) com assistência técnica do parceiro de implementação...

Nasopharyngeal carriage of Streptococcus pneumoniae among HIV-infected and -uninfected children <5 years of age before introduction of pneumococcal conjugate vaccine in Mozambique

PLos ONE; 13 (2), 2018
Nasopharyngeal carriage is a precursor for pneumococcal disease and can be useful for evaluating pneumococcal conjugate vaccine (PCV) impact. We studied pre-PCV pneumococcal carriage among HIV-infected and -uninfected children in Mozambique. Between October 2012 and March 2013, we enrolled HIV-infected c...

Health and socio-demographic profile of women of reproductive age in rural communities of southern Mozambique

PLos ONE; 13 (2), 2018
Reliable statistics on maternal morbidity and mortality are scarce in low and middle-income countries, especially in rural areas. This is the case in Mozambique where many births happen at home. Furthermore, a sizeable number of facility births have inadequate registration. Such information is crucial fo...

Evidence for chikungunya and dengue transmission in Quelimane, Mozambique: Results from an investigation of a potential outbreak of chikungunya virus

PLos ONE; 13 (2), 2018
Background: In January 2016, health authorities from Zambézia province, Mozambique reported the detection of some patients presenting with fever, arthralgia, and a positive result for chikungunya in an IgM-based Rapid Diagnostic Test (RDT). We initiated a study to investigate a potential chikungunya out...

Identifying Immune Correlates of Protection Against Plasmodium falciparum Through a Novel Approach to Account for Heterogeneity in Malaria Exposure

Clin. infect. dis; 66 (4), 2018
Background: A main criterion to identify malaria vaccine candidates is the proof that acquired immunity against them is associated with protection from disease. The age of the studied individuals, heterogeneous malaria exposure, and assumption of the maintenance of a baseline immune response can confound...

Inquérito de indicadores de imunização, Malária e HIV/SIDA em Moçambique (IMASIDA) 2015

O presente relatório do Inquérito de Indicadores de Imunização, Malária e HIV/SIDA apresenta informações sobre a fecundidade; gravidez e maternidade na adolescência; preferências de fecundidade; planeamento familiar; consultas pré-natais; assistência ao parto; vacinação de crianças; infecç...

Combination of indoor residual spraying with long-lasting insecticide-treated nets for malaria control in Zambezia, Mozambique: a cluster randomised trial and cost-effectiveness study protocol

BMJ glob. health; 3 (1), 2018
Background Most of the reduction in malaria prevalence seen in Africa since 2000 has been attributed to vector control interventions. Yet increases in the distribution and intensity of insecticide resistance and higher costs of newer insecticides pose a challenge to sustaining these gains. Thus, endemic ...

Invasive bacterial disease trends and characterization of group B streptococcal isolates among young infants in southern Mozambique, 2001-2015

PLoS One; 13 (1), 2018
Maternal group B streptococcal (GBS) vaccines under development hold promise to prevent GBS disease in young infants. Sub-Saharan Africa has the highest estimated disease burden, although data on incidence and circulating strains are limited. We described invasive bacterial disease (IBD) trends among inf...

Drug-resistant polymorphisms and copy numbers in plasmodium falciparum, mozambique, 2015

One of the fundamental steps toward malaria control is the use of antimalarial drugs. The success of antimalarial treatment can be affected by the presence of drug-resistant populations of Plasmodium falciparum. To assess resistance, we used molecular methods to examine 351 P. falciparum isolates collect...

Early diagnosis of preeclampsia using placental growth factor: An operational pilot study in Maputo, Mozambique

n well-resourced settings, reduced circulating maternal free placental growth factor (PlGF) aids in either predicting or confirming the diagnosis of preeclampsia, fetal growth restriction, stillbirth, preterm birth, and delivery within 14 days of testing when pre-eclampsia is suspected. This operational ...