Chambal, Lúcia Mabalane;
Gudo, Eduardo Samo;
Carimo, Awa;
Real, Rita Corte;
Mabunda, Nédio;
Maueia, Cremildo;
Vubil, Adolfo;
Zicai, Ana Flora;
Bhatt, Nilesh;
Antunes, Francisco.
Background HIV/ HBV coinfected patients are at high risk of developing chronic HBV infection, liver cirrhosis and hepatocellular carcinoma. In Mozambique, where HIV prevalence is one of the highest in the world, HIV-infected patients are scarcely characterized in terms of HBV coinfection and 3TC-resistan...
Background: Achieving the United Nations Sustainable Development Goals in sub-Saharan Africa will require substantial improvements in the coverage and performance of primary health care delivery systems. Projects supported by the Doris Duke Charitable Foundation's (DDCF) African Health Initiative (AHI) c...
Background: The Doris Duke Charitable Foundation's African Health Initiative supported the implementation of Population Health Implementation and Training (PHIT) Partnership health system strengthening interventions in designated areas of five countries: Ghana, Mozambique, Rwanda, Tanzania, and Zambia. A...
Background: Well-functioning health systems need to utilize data at all levels, from the provider, to local and national-level decision makers, in order to make evidence-based and needed adjustments to improve the quality of care provided. Over the last 7 years, the Doris Duke Charitable Foundation's Afr...
Background: Despite global efforts to increase health workforce capacity through training and guidelines, challenges remain in bridging the gap between knowledge and quality clinical practice and addressing health system deficiencies preventing health workers from providing high quality care. In many dev...
Background: High-quality data are critical to inform, monitor and manage health programs. Over the seven-year African Health Initiative of the Doris Duke Charitable Foundation, three of the five Population Health Implementation and Training (PHIT) partnership projects in Mozambique, Rwanda, and Zambia in...
Chissumbam, raquel, matavele;
Namalango, eduardo;
Maphossa, vânia;
Macicame, ivalda;
Bhatt, nilesh;
Polyak, christina;
Michael, nelson;
Jani, ilesh, v;
Kestens, luc.
Background: The acute phase of HIV infection is characterized by massive depletion of CD4 T cells, high viral plasma levels and pronounced systemic immune activation. Regulatory T cells (Tregs) have the potential to control systemic immune activation but also to suppress antigen specific T and B cell res...
Linfócitos T CD4-Positivos/citologia,
Citometria de Fluxo,
Fatores de Transcrição Forkhead/imunologia,
Infecções por HIV/imunologia,
HIV-1/imunologia,
Replicação Viral,
Carga Viral,
Linfócitos T CD4-Positivos/virologia,
Linfócitos T CD4-Positivos/imunologia,
Infecções por HIV/virologia,
Fator de Transcrição Ikaros/genética,
Antígenos Secundários de Estimulação de Linfócitos,
Linfócitos T Reguladores/imunologia,
Linfócitos T Reguladores/virologia,
Compartimentos de Replicação Viral/imunologia,
Moçambique
Jordan, M Michael;
Penazzato, Martina;
Cournil, Amandine;
Vubil, Adolfo;
Jani, Ilesh;
Hunt, Gilian;
Maphalala, Gudo;
Carmona, Sergio;
Mthethwa, Nobuhle;
Watera, Christine;
Kaleebu, Pontiano;
Musanhu, Christine Chaknyuka;
Mtapuri-Zinyowera, Sekasai;
Dzangare, Janet;
Peeters, Martine;
Yang, Chunfu;
Parkin, Iveil;
Bertagnolio, Silvia.
Background. Programs for the prevention of mother-to-child transmission (PMTCT) of human immunodeficiency virus (HIV) have been scaled up in many low- and middle-income countries. However, HIV drug resistance (HIVDR) data among HIV-1– infected young children remain limited.
Methods. Surveys of pretreat...
Ao longo da historia da medecina, particularmente durante a ultima metade do século xx, e inicio deste, assistiu-se a uma fragmentanção progressiva dos conhecimentos médicos, numa vasta gama de árias de diferenciação da arte e ciência de tratar.
Aclassificação destas árias não é uniforme en...
Background: Concerning gaps in the HIV care continuum compromise individual and population health. We evaluated a combination intervention strategy (CIS) targeting prevalent barriers to timely linkage and sustained retention in HIV care in Mozambique.
Methods and findings: In this cluster-randomized tria...
Fármacos Anti-HIV/administração & dosagem,
Análise por Conglomerados,
Terapia Combinada,
Intervenção Médica Precoce/métodos,
Seguimentos,
Infecções por HIV/diagnóstico,
HIV-1/efeitos dos fármacos,
Comportamentos Relacionados com a Saúde,
Motivação,
Cooperação do Paciente,
Epidemiologia,
Terapêutica,
Moçambique,
Infecções por HIV/terapia
