Chissumbam, raquel, matavele;
Namalango, eduardo;
Maphossa, vânia;
Macicame, ivalda;
Bhatt, nilesh;
Polyak, christina;
Michael, nelson;
Jani, ilesh, v;
Kestens, luc.
Background: The acute phase of HIV infection is characterized by massive depletion of CD4 T cells, high viral plasma levels and pronounced systemic immune activation. Regulatory T cells (Tregs) have the potential to control systemic immune activation but also to suppress antigen specific T and B cell res...
Linfócitos T CD4-Positivos/citologia,
Citometria de Fluxo,
Fatores de Transcrição Forkhead/imunologia,
Infecções por HIV/imunologia,
HIV-1/imunologia,
Replicação Viral,
Carga Viral,
Linfócitos T CD4-Positivos/virologia,
Linfócitos T CD4-Positivos/imunologia,
Infecções por HIV/virologia,
Fator de Transcrição Ikaros/genética,
Antígenos Secundários de Estimulação de Linfócitos,
Linfócitos T Reguladores/imunologia,
Linfócitos T Reguladores/virologia,
Compartimentos de Replicação Viral/imunologia,
Moçambique
Voronin, yegor;
Jani, ilesh;
Graham, barney, s;
Cunningham, coleen, k;
Mofenson, lynne, m;
Musoke, philippa, m;
Permar, sallie, r;
Scarlatti, gabriella.
Globally, 150,000 new paediatric human immunodeficiency virus type 1 (HIV-1) infections occurred in 2015. There remain complex challenges to the global elimination of paediatric HIV-1 infection. Thus, for the global community to achieve elimination of new paediatric HIV-1 infections, innovative approache...
HIV-1,
HIV-1/imunologia,
Vacinas contra a AIDS/administração & dosagem,
Anticorpos Anti-HIV,
Vacinas contra a AIDS/imunologia,
Infecções por HIV,
Anticorpos Neutralizantes/imunologia,
Anticorpos Anti-HIV/imunologia,
Infecções por HIV/imunologia,
Infecções por HIV/prevenção & controle,
Infecções/virologia,
Transmissão Vertical de Doenças Infecciosas/prevenção & controle
Jordan, M Michael;
Penazzato, Martina;
Cournil, Amandine;
Vubil, Adolfo;
Jani, Ilesh;
Hunt, Gilian;
Maphalala, Gudo;
Carmona, Sergio;
Mthethwa, Nobuhle;
Watera, Christine;
Kaleebu, Pontiano;
Musanhu, Christine Chaknyuka;
Mtapuri-Zinyowera, Sekasai;
Dzangare, Janet;
Peeters, Martine;
Yang, Chunfu;
Parkin, Iveil;
Bertagnolio, Silvia.
Background. Programs for the prevention of mother-to-child transmission (PMTCT) of human immunodeficiency virus (HIV) have been scaled up in many low- and middle-income countries. However, HIV drug resistance (HIVDR) data among HIV-1– infected young children remain limited.
Methods. Surveys of pretreat...
Ao longo da historia da medecina, particularmente durante a ultima metade do século xx, e inicio deste, assistiu-se a uma fragmentanção progressiva dos conhecimentos médicos, numa vasta gama de árias de diferenciação da arte e ciência de tratar.
Aclassificação destas árias não é uniforme en...
Background: Concerning gaps in the HIV care continuum compromise individual and population health. We evaluated a combination intervention strategy (CIS) targeting prevalent barriers to timely linkage and sustained retention in HIV care in Mozambique.
Methods and findings: In this cluster-randomized tria...
Fármacos Anti-HIV/administração & dosagem,
Análise por Conglomerados,
Terapia Combinada,
Intervenção Médica Precoce/métodos,
Seguimentos,
Infecções por HIV/diagnóstico,
HIV-1/efeitos dos fármacos,
Comportamentos Relacionados com a Saúde,
Motivação,
Cooperação do Paciente,
Epidemiologia,
Terapêutica,
Moçambique,
Infecções por HIV/terapia
Floridia, Marco;
Ciccacci, Fausto;
Andreotti, Mauro;
Hassane, Archa;
Sidumo, Zita;
Magid, Nurja A;
Sotomane, Horacio;
David, Muhlavasse;
Mutemba, Elsa;
Cebola, Junia;
Mugunhe, Remigio José;
Riccardi, Fabio;
Marazzi, Maria Cristina;
Giuliano, Marina;
Palombi, Leonardo;
Mancinelli, Sandro.
Tuberculosis is a major health concern in several countries, and effective diagnostic algorithms for use in human
immunodeficiency virus (HIV)–positive patients are urgently needed.
Methods. At prescription of antiretroviral therapy, all patients in 3 Mozambican health centers were screened for tubercu...
Algoritmos,
Terapia Antirretroviral de Alta Atividade,
Antituberculosos,
Infecções por HIV/tratamento farmacológico,
Lipopolissacarídeos,
Técnicas de Diagnóstico Molecular,
Moçambique,
Mycobacterium tuberculosis,
Prevalência,
Sensibilidade e Especificidade,
Tuberculose Pulmonar/diagnóstico,
Escarro
Introduction: The scale-up of effective HIV viral load (VL) testing is an urgent public health priority. Implementation of testing is supported by the availability of accurate, nucleic acid based laboratory and point-of-care (POC) VL technologies and strong WHO guidance recommending routine testing to id...
The common theme and aim for this thesis was to explore the epidemiology and the diagnostic possibilities of patients with non-malarial febrile infections of tropical origin, with both the individual patient perspective and the more general public health aspects in focus. Analysis from two study areas, S...
Gupta, himanshu;
Matambisso, gloria;
Galatas, beatriz;
Simone, wilson;
Nhamussua, lidia;
Cisteró, pau;
Cunningham, jane;
Rabinovich, N regina;
Saute, francisco;
Alonso, pedro L;
Aide, pedro;
Mayor, Alfredo.
Background: Malaria programmes use Plasmodium falciparum histidine-rich protein-2 (PfHRP2) based rapid diagnos tic tests (RDTs) for malaria diagnosis. The deletion of this target antigen could potentially lead to misdiagnosis, delayed treatment and continuation of active transmission. Methods: Plasmodium...
Martins-Fonteyn, Emilia;
Loquiha, Osvaldo;
Baltazar, Cynthia;
Thapa, Subash;
University of California, San Francisco – USA, of Global Health Sciences;
Raimundo, Ines;
Hens, Niel;
Aerts, Marc;
Meulemans, Herman;
Degomme, Olivier;
Wouters, Edwin.
Background: Information dealing with social and behavioural risk factors as well as their mechanisms among
Mozambican migrants working in South African mines remains undocumented. This study aims to understand the
various factors influencing HIV-related risk behaviours and the resulting HIV positive stat...
