Resultados: 11

Estudo piloto de tripanossomose em cães na região da ponta do ouro e machangulo, moçambique
Pilot study of trypanosomosis in dogs in the region of ponta do ouro and machangulo, mozambique

A Tripanossomose é uma doença causada por tripanossoma, protozoários flagelados transmitidos por moscas pertencentes ao género Glossina spp., vulgarmente chamadas moscas Tsé-Tsé. A distribuição geográfica da Tripanossomose observa-se sobretudo na África subsaariana, onde afeta quer humanos, cau...

Assessment of diagnosis and treatment practices of diarrhoea in children under five in Maputo-Mozambique

Background: Although diagnosis and treatment of diarrhoea are considered easy, statistics show that 525,000 children worldwide die annually due to diarrhoea, 90% of the deaths are in Sub-Saharan Africa and South Asia, and Mozambique account for 6.9%. Assessment of practices of diagnosis and treatment of ...

Two Randomized Trials of Neutralizing Antibodies to Prevent HIV-1 Acquisition

N. Engl. j. med; 384 (11), 2021
BACKGROUND—Whether a broadly neutralizing antibody (bnAb) can be used to prevent human immunodeficiency virus type 1 (HIV-1) acquisition is unclear. METHODS—We enrolled at-risk cisgender men and transgender persons in the Americas and Europe in the HVTN 704/HPTN 085 trial and at-risk women in sub-Sah...

Caracterização molecular enterovĺrus detectados em crianças com diarreia aguda e amostras ambientais em Moçambique
Molecular characterization of enteroviruses detected in children with acute diarrhea and environmental samples in Mozambique

Os enterovírus (EV) são vírus de transmissão predominantemente entérica, presentes em todas as partes do mundo e são agentes etiológicos de infecções que variam de casos assintomáticos a casos de gastroenterite aguda (GA) e infecções no sistema nervoso central. Devido aos diferentes rumos que...

Review article on cardiovascular diseases in low- and middle-income countries

Parasit. vectors; (), 2020
Endomyocardial fibrosis (EMF) is a poverty-related disease of unknown origin that afflicts predominantly young people of certain rural areas in low-income countries and can be used to expose global disparities in cardiovascular research. Despite affecting predominantly young people and causing high morbi...

HIV development assistance and adult mortality in Africa

JAMA; 16 (307), 2016
Context: The effect of global health initiatives on population health is uncertain. Between 2003 and 2008, the US President's Emergency Plan for AIDS Relief (PEPFAR), the largest initiative ever devoted to a single disease, operated intensively in 12 African focus countries. The initiative's effect on al...

A public health paradox: the women most vulnerable to malaria are the least protected

PloS med; 13 (5), 2016
Raquel Gonzalez and colleagues highlight an urgent need to evaluate antimalarials that can be safely administered to HIV-infected pregnant women on antiretroviral treatment and cotrimoxazole prophylaxis. African HIV-infected pregnant women are the most vulnerable population group to malaria infection. ...

Intermittent preventive treatment of malaria in pregnancy with mefloquine in HIV-negative women: a multicentre randomized controlled trial

PloS med; 11 (9), 2014
Background: Intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) is recommended by WHO to prevent malaria in African pregnant women. The spread of SP parasite resistance has raised concerns regarding long-term use for IPT. Mefloquine (MQ) is the most promising of avai...

The effect of hookworm infection and urinary schistosomiasis on blood hemoglobin concentration of schoolchildren living in northern mozambique

This study aims to assess the association between schistosomiasis and hookworm infection with hemoglobin levels of schoolchildren in northern Mozambique. Through a cross-sectional survey, 1,015 children from five to 12 years old in the provinces of Nampula, Cabo Delgado and Niassa were studied. Hookworm ...

Estudo da Diversidade Genética e Mutações de Resistência do Hiv aos Arv S na Região Norte de Moçambique

O HIV é um retrovírus de evolução rápida caracterizado por uma enorme diversidade genética. Os eventos de recombinação durante a transcrição reversa, a elevada taxa de replicação viral e a incapacidade da transcriptase reversa em corrigir erros de incorporação de nucleotídeos nas cadeias e...