AAge interactions in the development of naturally acquired immunity to plasmodium falciparum and its clinical presentation
PloS med; 4 (7), 2007
Background
Naturally acquired malaria immunity has many determinants and, in the absence of immunological markers of protection, studies assessing malaria incidence through clinical endpoints remain an approach to defining immunity acquisition. We investigated the role of age in disease incidence and th...
Fatores Etários, Anemia, Antígenos de Protozoários/imunologia, Anemia/prevenção & controle, Anemia/imunologia, Dapsona/uso terapêutico, Quimioterapia Combinada, Malária Falciparum/imunologia, Malária Falciparum/prevenção & controle, Malária Falciparum/epidemiologia, Plasmodium falciparum/imunologia, Plasmodium falciparum/efeitos dos fármacos, Tanzânia/epidemiologia, Pirimetamina/uso terapêutico, Resultado do Tratamento