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Efficacy and safety of dihydroartemisinin-piperaquine for treatment of Plasmodium falciparum uncomplicated malaria in adult patients on antiretroviral therapy in Malawi and Mozambique: an open label non-randomized interventional trial

Sevene, esperança; Banda, clifford G; Mukaka, mavuto; Maculuve, sonia; Vala, anifa; Macuacua, salésio; Piqueras, mireia; Phiri, linda kalilani; Mallewa, jane; Terlouw, dianne J; Khoo, saye H; Lalloo, david G; Mwapasa, victor.
Malar. j. (Online); 18 (1), 2019
Background: HIV-infected individuals on antiretroviral therapy (ART) require treatment with artemisinin-based combination therapy (ACT) when infected with malaria. Dihydroartemisinin–piperaquine (DPQ) is recommended for treatment of Plasmodium falciparum malaria, but its efcacy and safety has not been ...
Artemisininas/efeitos adversos, Antimaláricos/efeitos adversos, Antirretrovirais/uso terapêutico, Benzoxazinas/uso terapêutico, Ciclopropanos, Malária Falciparum/prevenção & controle, Moçambique, Nevirapina/uso terapêutico, Plasmodium falciparum/fisiologia
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Nevirapine or efavirenz for tuberculosis and HIV coinfected patients: exposure and virological failure relationship

Bhatt, Nilesh B; Baudin , Elisabeth; Meggi, Bindiya; Silva, Carlota da; Tran, Aurélie Barrai; Furlan, Valérie; Grinsztejn, Beatriz; Bonnet, Maryline; Taburet 5, Anne-Marie.
J. antimicrob. chemother; 70 (1), 2015
Objectives: We describe nevirapine and efavirenz exposure on and off tuberculosis treatment and consequences for virological efficacy and tolerance in patients included in the ANRS 12146/12214-CARINEMO trial. Methods: Participants were randomly selected to receive either nevirapine at 200 mg twice daily...
Alcinos, Terapia Antirretroviral de Alta Atividade/métodos, Antituberculosos/uso terapêutico, Benzoxazinas/uso terapêutico, Ciclopropanos, Infecções por HIV/terapia, Tolerância a Medicamentos, Fármacos Anti-HIV/uso terapêutico, Infecções/complicações, Nevirapina/uso terapêutico, Tuberculose/terapia, Tuberculose/complicações, Resultado do Tratamento, Moçambique
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Pharmacokinetics of Rifampin and Isoniazid in Tuberculosis-HIVCoinfected Patients Receiving Nevirapine- or Efavirenz-Based Antiretroviral Treatment
Pharmacokinetics of Rifampin and Isoniazid in Tuberculosis-HIVCoinfected Patients Receiving Nevirapine- or Efavirenz-Based Antiretroviral Treatment

Amin, A; Baudin, E; Meggi, B; Silva, C; Furlan, B; Grinsztejr, B; Barril-Tran, A; Boné, M; Tabura, A. M.
Antimicrob. agents chemother; 58 (6), 2014
This is a substudy of the Agence Nationale de Recherches sur le Sida et les Hépatites Virales (ANRS) Comparison of Nevirapine and Efavirenz for the Treatment of HIV-TB Co-infected Patients (ANRS 12146-CARINEMO) trial, which assessed the pharmacokinetics of rifampin or isoniazid with or without the coadm...
HIV/efeitos dos fármacos, Antituberculosos/administração & dosagem, Benzoxazinas, Mycobacterium, Mycobacterium tuberculosis/efeitos dos fármacos, Tuberculose/tratamento farmacológico, Síndrome da Imunodeficiência Adquirida/epidemiologia, Soroprevalência de HIV/tendências, Hepatite/diagnóstico, Antígenos CD4/efeitos dos fármacos, Moçambique/epidemiologia
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