Impact of age of first exposure to Plasmodium falciparum on antibody responses to malaria in children: a randomized, controlled trial in Mozambique
Malar. j. (Online); 13 (121), 2014
Background: The impact of the age of first Plasmodium falciparum infection on the rate of acquisition of immunity to malaria and on the immune correlates of protection has proven difficult to elucidate. A randomized, double-blind, placebo-controlled trial using monthly chemoprophylaxis with sulphadoxine-...
Malária Falciparum/imunologia, Moçambique/epidemiologia, Pirimetamina/uso terapêutico, Sulfadoxina/uso terapêutico, Imunidade Adaptativa, Antígenos de Protozoários/imunologia, Exposição Ambiental, Malária Falciparum/prevenção & controle, Malária Falciparum/epidemiologia, Malária Falciparum/parasitologia, Ensaio de Imunoadsorção Enzimática, Eritrócitos/parasitologia, Eritrócitos/imunologia, Quimioprevenção