Castro, Lucia Carratala;
Ssengooba, Willy;
Kay, Alex;
Acácio, Sozinho;
Ehrlich, Joanna;
DiNardo, Andrew R;
Shiba, Shiba;
Nsubuga, Joachim K;
Munguambe, Shilzia;
Cervera, Belén Saavedra;
Manjate, Patricia;
Mulengwa, Durbbin;
Sibandze, Busizwe;
Ziyane, Mangaliso;
Kasule, George;
Mambuque, Edson;
Sekadde, Moorine Penninah;
Wobudeya, Eric;
Joloba, Moses L;
Heyckendorf, Jan;
Lange, Christoph;
Hermans, Sabine;
Mandalakas, Anna;
Basteiro, Alberto L García;
Varela, Elisa Lopez.
Background: Tuberculosis (TB) is a major cause of mortality worldwide. Children and people living with HIV (PLHIV) have an increased risk of mortality, particularly in the absence of rapid diagnosis. The main challenges of diagnosing TB in these populations are due to the unspecific and paucibacillary di...
Infecções por HIV/complicações,
Mycobacterium tuberculosis,
Tuberculose/diagnóstico,
Tuberculose Pulmonar/diagnóstico,
Infecções por HIV/diagnóstico,
Estudos Multicêntricos como Assunto,
Estudos Prospectivos,
Sensibilidade e Especificidade,
Essuatíni,
Moçambique,
Uganda
Schacht, daroline de;
Nhacule, edna;
Belo, celso;
Young, peter w;
Bhatt, nilesh;
Júnior, faustino;
Gusmão, eduarda pimentel de;
Muquingue, humberto;
Muteerwa, ana;
Bila, Dulce;
Ouenzar, mohammed a;
Madede, tavares;
Cumbane, reginalda;
Amorim, gustavo;
Viegas, edna.
Introduction: As COVID-19 continues to spread globally and within Mozambique, its impact among immunosuppressed persons, specifically persons living with HIV (PLHIV), and on the health system is unknown in the country. The 'COVid and hIV' (COVIV) study aims to investigate: (1) the seroprevalence and sero...
Martinez, Francisco Jose;
Massinga, Arsenia J;
Jesus, Áuria;
Ernesto, Rita M;
Jiménez, Pablo Cano;
Oms, Álvaro Chiner;
Navarro , Inmaculada Gómez;
Fernández, Marina Guillot;
Guinovart, Caterina;
Sitoe, António;
Vubil, Delfino;
Bila, Rubão;
Gujamo, Rufino;
Enosse, Sónia;
Serrano, Santiago Jiménez;
Puente, Manuela Torres;
Comas, Iñaki;
Mandomando, Inácio;
G López, Mariana;
Mayor, Alfredo.
From the start of the SARS-CoV-2 outbreak, global sequencing efforts have generated an unprecedented amount of genomic data. Nonetheless, unequal sampling between high-income and low-income countries hinders the implementation of genomic surveillance systems at the global and local level. Filling the kno...
Levy, karen;
Garn, joshua V;
Cumbe, zaida adriano;
Muneme, bacelar;
Fagnant-Sperati, christine s;
Hubbard, Sydney;
Júnior, antonio;
Manuel, joão luís;
Mangamela, Magalhães;
McGunegill, sandy;
Miller-Petrie, molly k;
Snyder, jedidiah s;
Victor, courtney;
Waller, lance a;
Konstantinidis, konstantinos t;
Clasen, thomas f;
Brown, joe;
Nalá, rassul;
Freeman, matthew c.
Introduction: Despite clear linkages between provision of clean water and improvements in child health, limited information exists about the health impacts of large water infrastructure improvements in low-income settings. Billions of dollars are spent annually to improve urban water supply, and rigorou...
Abastecimento de Água/métodos,
Estudos de Coortes,
Comitês de Ética em Pesquisa,
Microbioma Gastrointestinal,
Humanos,
Lactente,
Moçambique,
Gravidez,
Estudos Prospectivos,
Doenças Transmitidas pela Água/transmissão,
d0148810
M'poca, Charles;
Osman, Nafissa Bique;
Arijama, Domingos;
Matingane, Benjamim;
Sitoé, Tomás;
Kenga, Darlene;
Lorenzoni, Cesaltina;
Luís, Elvira;
Pacagnella, Rodolfo de Carvalho;
Sacarlal, Jahit.
Although there is a significant increase of evidence regarding the prevalence and impact of COVID-19 on maternal and perinatal outcomes, data on the effects of the pandemic on the obstetric population in sub-Saharan African countries are still scarce. Therefore, the study aims were to assess the prevalen...
COVID-19/epidemiologia,
Morte Materna,
Moçambique/epidemiologia,
Parto,
Período Pós-Parto,
Complicações Infecciosas na Gravidez/diagnóstico,
Resultado da Gravidez/epidemiologia,
Nascimento Prematuro/epidemiologia,
Estudos Prospectivos,
SARS-CoV-2,
Complicações Infecciosas na Gravidez/epidemiologia
Cervera, Belén Saavedra;
López, Mariana G;
Chiner-Oms, Álvaro;
García, Ana Maria;
Cancino-Muñoz, Irving;
Torres-Puente, Manuela;
Villamayor, Luis;
Carlos Madrazo-Moya, Carlos;
Mambuque, Edson;
Sequera, Guilherme Victor;
Respeito, Durval;
Blanco, Sílvia;
Augusto, Orvalho;
López-Varela, Elisa;
Garcia-Basteiro, Alberto L;
Comas, Iñaki.
Genomic studies of the Mycobacterium tuberculosis complex (MTBC) might shed light on the dynamics of its transmission, especially in high-burden settings, where recent outbreaks are embedded in the complex natural history of the disease. To this end, we conducted a 1 year prospective surveillance-based ...
Introdução: A crescente carga global de Doenças Não Transmissíveis (DNTs) exige sistemas de vigilância que permitam acompanhar as tendências e avaliar o impacto de intervenções. O objectivo destes estudos foi testar modelos de vigilância hospitalar e comunitária de factores de risco e de DNTs....
Doença,
Doença Crônica,
Doenças Transmissíveis,
Doenças não Transmissíveis,
Encaminhamento e Consulta,
Estratégias de Saúde,
Estudos Longitudinais,
Estudos Prospectivos,
Hospitais,
Incidência,
Monitoramento Epidemiológico,
Moçambique,
Pilotos,
População Urbana,
Prevalência,
Risco,
Saúde,
Vigilância em Desastres,
Métodos,
tendências
Mayor, Alfredo;
Silva, Clemente;
Valbona, Eduard Rovira;
Feltrer, Arantxa Roca;
Bonnington, Craig;
Smith, Alexandra Wharton;
Greehouse, Bryan;
Bever, Caitlin;
Chidimatembue, Arlindo;
Guinovart, Caterina;
Proctor, Joshua L;
Rodrigues, Maria;
Canana, Neide;
Arnaldo, Paulo;
Boene, Simone;
Enosse, Sonia;
Saute, Francisco;
Candrinho, Baltazar.
Introduction: Genomic data constitute a valuable adjunct to routine surveillance that can guide programmatic decisions to reduce the burden of infectious diseases. However, genomic capacities remain low in Africa. This study aims to operationalise a functional malaria molecular surveillance system in Moz...
Background: Technological advances and high throughput biological assays can facilitate discovery science in biobanks from population cohorts, including pregnant women. Biological pathways associated with health outcomes differ depending on geography, and high-income country data may not generalise to lo...
Introduction: With improved access to anti-retroviral therapy (ART) the focus of HIV treatment is changing to reducing chronic co-morbidities and their effects, but guidelines for HIV care in many African countries do not include screening for cardiac disease. Our study aimed to determine the pattern of ...
