Martinez, Francisco Jose;
Massinga, Arsenia J;
Jesus, Áuria;
Ernesto, Rita M;
Jiménez, Pablo Cano;
Oms, Álvaro Chiner;
Navarro , Inmaculada Gómez;
Fernández, Marina Guillot;
Guinovart, Caterina;
Sitoe, António;
Vubil, Delfino;
Bila, Rubão;
Gujamo, Rufino;
Enosse, Sónia;
Serrano, Santiago Jiménez;
Puente, Manuela Torres;
Comas, Iñaki;
Mandomando, Inácio;
G López, Mariana;
Mayor, Alfredo.
From the start of the SARS-CoV-2 outbreak, global sequencing efforts have generated an unprecedented amount of genomic data. Nonetheless, unequal sampling between high-income and low-income countries hinders the implementation of genomic surveillance systems at the global and local level. Filling the kno...
Bero, Diocreciano Matias;
da Silva, Edson Elias;
Junior Ivanildo, Pedro de Sousa;
Nhassengo, Sheila António;
Machado, Raiana Scerni;
Bauhofer, Adilson Fernando Loforte;
Chilaúle, Jorfélia José;
Munlela, Benilde;
Guimarães, Esperança;
Moiane, Idalécia Cossa;
Sambo, Júlia;
Elda, Anapakala;
Cassocera, Marta;
Coutinho-Manhique, Lena;
Chissaque, Assucênio;
Langa, Jerônimo J;
Burlandy, Fernanda;
Deus, de Nilza.
Enteroviruses (EV) are predominantly enteric viruses, present in all parts of the world causing disease in humans with a broad spectrum of clinical presentations. The purpose of this study was to identify non-polio enteroviruses (NPEV) in stool samples collected from children with acute gastroenteritis (...
Munlela, Benilde;
João, eva d;
Donato, celeste m;
Strydom, amy;
Boene, simone s;
Chissaque , assucênio;
Bauhofer, adilson f. l;
Langa, jerónimo;
Cassocera, Marta;
Cossa-Moiane, Idalécia;
Chilaúle, jorfélia j;
O’Neill, hester g;
de Deus, nilsa.
Mozambique introduced the rotarix® vaccine (gsk biologicals, rixensart, belgium) into the na-tional immunization program in september 2015. Although g1p[8] was one of the most prevalent genotypes between 2012 and 2017 in mozambique, no complete genomes had been sequenced to date. here we report whole ge...
Jofrin, léa;
Goodman, steven m;
Wilkinson, david a;
Ramasindrazana, beza;
Lagadec, erwan;
Minter, gildas le;
Santos, andréa dos;
Schoeman, m corrie;
Sookhareea, rajendraprasad;
Tortosa, Pablo;
Gudo, eduardo s;
Mavingui, Patrick;
Lebarbenchon, camille.
Bats provide key ecosystem services such as crop pest regulation, pollination, seed dispersal, and soil fertilization. Bats are also major hosts for biological agents responsible for zoonoses, such as coronaviruses (CoVs). The islands of the Western Indian Ocean are identified as a major biodiversity hot...
Moçambique,
Prevalência,
Ilhas do Oceano Índico/epidemiologia,
Controle Social Formal,
Infecções por Coronavirus/epidemiologia,
Infecções por Coronavirus/veterinária,
Infecções por Coronavirus/virologia,
DNA Viral/genética,
Ecossistema,
Evolução Molecular,
Variação Genética,
Especificidade de Hospedeiro,
Filogenia,
Programas de Rastreamento,
Filogeografia/métodos,
RNA Polimerase Dependente de RNA,
Alphacoronavirus/genética,
Betacoronavirus/genética,
Quirópteros/virologia,
RNA Polimerase Dependente de RNA/genética,
Reação em Cadeia da Polimerase em Tempo Real,
Zoonoses/epidemiologia,
Zoonoses/virologia
Joao, eva dora;
Stroydon, amey;
Oneil g, hester;
Cumba, assa;
Cossecera, marta;
Acacio, sozinho;
Mandomando, inácio;
Motanyane, lithabiso;
Page, nicola;
Deus, nilsa de.
In Mozambique rotavirus (RV) was shown to be the greatest cause of acute diarrhoea in infants from 0 to 11 months, and in 2015, national rotavirus vaccination was introduced. As with other developing countries, there is very limited active strain characterisation. Rotavirus positive clinical specimens, c...
Gastroenterite/virologia,
Genótipo,
Infecções por Rotavirus/virologia,
Doença Aguda,
Filogenia,
Rotavirus/genética,
Antígenos Virais/genética,
Variação Genética,
Regulação Viral da Expressão Gênica,
Moçambique,
Epitopos/genética
Hoarau, flora;
Joffrin, léa;
Schoeman, m. corrie;
Lagadec, erwan;
Ramasindrazana, beza;
Santos, andréa dos;
Goodman, steven m;
Gudo, eduardo s;
mavingui, patrick;
Lebarbenchon, camille.
Astroviruses (AstVs) are responsible for infection of a large diversity of mammalian and avian species, including bats,
aquatic birds, livestock and humans. We investigated AstVs circulation in bats in Mozambique and Mayotte, a small
island in the Comoros Archipelago located between east Africa and Madag...
Enfuvirtide was the first fusion inhibitor approved by the Food and Drug Administration (FDA) in 2003 for HIV-1 infection in treatment-experienced patient. It is the first approved antiviral agent to attack the HIV life cycle in its early stages. For HIV fusion to occur, the HR1 and HR2 domains in the gp...
HIV-1/genética,
Sequência de Aminoácidos,
Fármacos Anti-HIV,
Análise por Conglomerados,
Farmacorresistência Viral,
Enfuvirtida,
Genótipo,
Proteína gp41 do Envelope de HIV/genética,
Infecções por HIV/virologia,
HIV-1/classificação,
Dados de Sequência Molecular,
Moçambique,
Mutação de Sentido Incorreto,
Fragmentos de Peptídeos,
Filogenia,
Polimorfismo Genético,
RNA Viral,
Alinhamento de Sequência,
Análise de Sequência de DNA,
Falha de Tratamento
Bila, Dulce Celina Adolfo;
Young, Pedro;
Merks, Harriet;
Vubil, Adolfo Salvador;
Mahomed, Mussagy;
Augusto, Angelo;
Abreu, Celina Monteiro;
Mabunda, Nédio Jonas;
Brooks, James, I;
Tanuri, Amilcar;
Jani, Ilesh Vinodrai.
Objective: InMozambique, highly active antiretroviral treatment (HAART) was introduced in 2004 followed by decentralizationandexpansion, resulting inamorethan20-fold increase incoverageby2009. ImplementationofHIV drugresistancethresholdsurveys (HIVDR-TS) iscrucial inorder tomonitor theemergenceof transmi...
Fármacos Anti-HIV/farmacologia,
Fármacos Anti-HIV/uso terapêutico,
Terapia Antirretroviral de Alta Atividade,
Moçambique,
Farmacorresistência Viral/genética,
Infecções por HIV/terapia,
Infecções por HIV/epidemiologia,
Infecções por HIV/virologia,
HIV-1/classificação,
HIV-1/efeitos da radiação,
HIV-1/genética,
Moçambique/epidemiologia,
Mutação,
Filogenia
Multiple-locus variable-number tandem repeat analysis (MLVA) is useful to establish transmission routes and sources of infections for various microorganisms including Mycobacterium tuberculosis complex (MTC). The recently released SITVITWEB database contains 12-loci Mycobacterial Interspersed Repetitive ...
Técnicas de Tipagem Bacteriana,
Teorema de Bayes,
Loci Gênicos/genética,
Genótipo,
Internacionalidade,
Sequências Repetitivas Dispersas/genética,
Repetições de Microssatélites/genética,
Mycobacterium tuberculosis/classificação,
Mycobacterium tuberculosis/genética,
Filogenia,
Filogeografia
Aide, Pedro;
Dobano, Carlota;
Sacarlal, Jahit;
Aponte, John J;
Mandomando, Inácio;
Guinovart, Caterina;
Bassat, Quique;
Renom, Montse;
Puyol, Laura;
Macete, Eusebio;
Herreros, Esperanza;
Leach, Amanda;
Dubois, Marie-Claude;
Demoitie, Marie-Ange;
Lirvrens, Marc;
Vekemans, Johan;
Loucq, Christian L;
Ballou, W. Ripley;
Cohen, Joe;
Alonso, Pedro L.
Previous studies with the malaria vaccine RTS,S/AS02A in young children in a malaria endemic area of Mozambique have shown it to have a promising safety profile and to reduce the risk of Plasmodium falciparum infection and disease. In this study, we assessed the antibody responses to the P. falciparum an...
