Sub-Saharan Africa concentrates the burden of HIV and the highest adolescent fertility rates. However, there is limited information about the impact of the interaction between adolescence and HIV infection on maternal health in the region. Data collected prospectively from three clinical trials conducted...
Context: The effect of global health initiatives on population health is uncertain. Between 2003 and 2008, the US President's Emergency Plan for AIDS Relief (PEPFAR), the largest initiative ever devoted to a single disease, operated intensively in 12 African focus countries. The initiative's effect on al...
Introduction: Despite significant gains in access to early infant diagnosis (EID) over the past decade, most HIV-exposed infants still do not get tested for HIV in the first two months of life. For those who are tested, the long turnaround time between when the sample is drawn and when the results are re...
During 2004-2009, >12,000 children (<15 years old) initiated antiretroviral therapy (ART) in Mozambique. Nationally representative outcomes and temporal trends in outcomes were investigated.
Methods: Rates of death, loss to follow-up (LTFU) and attrition (death or LTFU) were evaluated in a nationally re...
We studied patient outcomes by type of referral site following 2 years of combination antiretroviral therapy
(cART) during scale-up from June 2006 to July 2011 in Mozambique’s rural Zambe´zia Province. Loss to followup (LTFU) was defined as no contact within 60 days after scheduled medication pickup. ...
Background: Co-infection with falciparum malaria and HIV-1 increases the severity and mortality of both infections in unstable malaria-transmission areas. In contrast, in stable transmission areas, HIV co-infection increases the severity of both infections but has not been found to influence malaria mort...
Background: The potential impact of HIV-1 on falciparum malaria has been difficult to determine
because of diagnostic problems and insufficient epidemiological data.
Methods: In a prospective, cross-sectional study, clinical and laboratory data was registered
consecutively for all adults admitted to a me...
