RDSM – Rede de Documentação sobre Saúde em Moçambique

Risk of extended viral resistance in human immunodeficiency virus-1-infected Mozambican children after first-line treatment failure

Vaz, paula; Chaix, marie-laure; Jani, ilesh; Macassa, eugenia; Bila, Dulce; Vubil, Adolfo; Anderson, Soren; Rouzioux, christine, pharmD; Briand, nelly; Blanche, stephane.

Pediatr. infect. dis. j; 28 (12), 2009

Background: Resistant virus may be selected by sub-optimal control of HIV-1 replication during antiretroviral treatment. The incidence and profile of resistance in children receiving World Health Organization-recommended treatment remains to be evaluated on a large scale. Goals: Assessment of the frequen...

Resistência a Medicamentos, HIV-1/genética, Fármacos Anti-HIV, Infecções por HIV/sangue, Replicação Viral, Análise de Variância, HIV-1/fisiologia, Infecções por HIV/terapia, Infecções por HIV/virologia, Inibidores da Transcriptase Reversa/farmacologia, Inibidores da Transcriptase Reversa/uso terapêutico, Fármacos Anti-HIV/farmacologia, Fármacos Anti-HIV/uso terapêutico, Falha de Tratamento, Moçambique

Texto completo

Molecular Epidemiology and Trends in HIV-1 Transmitted Drug Resistance in Mozambique 1999–2018

Viruses; 14 (9), 1992

HIV drug resistance (HIVDR) can become a public health concern, especially in low- and middle-income countries where genotypic testing for people initiating antiretroviral therapy (ART) is not available. For first-line regimens to remain effective, levels of transmitted drug resistance (TDR) need to be m...