Optimal antituberculosis therapy is essential for favorable
clinical outcomes. Peak plasma concentrations of first-line
antituberculosis drugs in infants with living HIV receiving
WHO-recommended dosing were low compared with reference values for adults, supporting studies on increased doses of
first-lin...
A epidemia do HIV continua a ser um grande desafio de Saúde Pública em Moçambique,
com cerca de 2,4 milhões de pessoas vivendo com o vírus e uma prevalência de 12,5% entre
os adultos (SPECTRUM 6.26, 2023). O país fez progressos significativos na sua resposta ao
longo dos anos, com maior enfoque pa...
Introduction: Despite clear linkages between provision of clean water and improvements in child health, limited information exists about the health impacts of large water infrastructure improvements in low-income settings. Billions of dollars are spent annually to improve urban water supply, and rigorou...
Attaining the goal of reducing the global malaria burden is threatened by recent setbacks in maintaining the effectiveness of vector control interventions partly due to the emergence of pyrethroid resistant vectors. One potential strategy to address these setbacks could be combining indoor residual spray...
Background: Malaria is one of the most widespread and deadly diseases worldwide and large majority of malaria cases and deaths occurs in Africa. Efforts to develop an effective vaccine against malaria are underway and several vaccine prototypes are on different clinical trial phases.Objective: As many su...
Abstract. Globally, approximately 5.9 million children under 5 years of age died in 2015, a reduction of over 50% since 1990. Millennium Development Goal 4 established the goal of reducing child mortality by two-thirds by 2015. Multiple countries have surpassed this goal; however, regional and within-cou...
Measles elimination has been on the World Health Organization agenda for the last fifteen
years. Progress towards elimination has been made. However, it has not been uniform around
the world. On the African continent, the vaccine coverage rate is the lowest in the world and
the disease burden is the high...
