Molecular surveillance for polymorphisms associated with artemisinin-based combination therapy resistance in Plasmodium falciparum isolates collected in Mozambique, 2018
Malar. j. (Online); 20 (1), 2021
Background: Due to the threat of emerging anti-malarial resistance, the World Health Organization recommends incorporating surveillance for molecular markers of anti-malarial resistance into routine therapeutic efficacy studies (TESs). In 2018, a TES of artemether-lumefantrine (AL) and artesunate-amodiaq...
Antimaláricos/farmacologia, Antimaláricos/uso terapêutico, Artemisininas/farmacologia, Artemisininas/uso terapêutico, Resistência a Medicamentos/genética, Quimioterapia Combinada, Marcadores Genéticos, Plasmodium falciparum/efeitos da radiação, Plasmodium falciparum/genética, Plasmodium falciparum/isolamento & purificação, Polimorfismo Genético/genética, Moçambique