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Reduced Placental Transfer of Antibodies Against a Wide Range of Microbial and Vaccine Antigens in HIV-Infected Women in Mozambique

Alonso, Selena; Vudal, Marta; Olalla, Gemma Ruiz; Gonzelez, Raquel; Manaca, M. Nelia; Jairoce, Chenjerai; Santiago, Chenjerai; Balcells, Reyes; Vala, Anifa; Ruperez, María; Cistero, Pau; Soro, Laura Fuente; Cova, Marta; Angov, Evelina; Nhacolo, Arsenio; Sevene, Esperança; Aponte, John J; Macete, Eusebio; Aguilar, Ruth; Mayor, Alfredo; Menendez, Clara; Dobano, Carlota; Moncunil, Gemma.
Front. immunol; 12 (), 2021
Transplacental transfer of antibodies is essential for conferring protection in newborns against infectious diseases. We assessed the impact of different factors, including gestational age and maternal infections such as HIV and malaria, on the efficiency of cord blood levels and placental transfer of Ig...
HIV, Imunoglobulina G, Anticorpos Monoclonais, Malária, Escolas Maternais, Patógenos Transmitidos pelo Sangue, d0053120, Placenta/imunologia, Placenta/metabolismo, Gravidez, Infecções por HIV/virologia
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Reduced Placental Transfer of Antibodies Against a Wide Range of Microbial and Vaccine Antigens in HIV-Infected Women in Mozambique

Alonso, Selena; Vudal, Marta; Olalla, Gemma Ruiz; Gonzelez, Raquel; Manaca, M Nelia; Jairoce, Chenjerai; Balcells, Reyes; Vala, Anifa; Ruperez, María; Soro, Laura Fuente; Cova, Marta; Angov, Evelina; Nhacolo, Arsenio; Sevene, Esperança; Aponte, John J; Macete, Eusebio; Dobano, Carlota; Moncunil, Gemma.
Front. immunol; 12 (), 2021
Transplacental transfer of antibodies is essential for conferring protection in newborns against infectious diseases. We assessed the impact of different factors, including gestational age and maternal infections such as HIV and malaria, on the efficiency of cord blood levels and placental transfer of Ig...
Anticorpos/imunologia, Antígenos/imunologia, Terapia Antirretroviral de Alta Atividade, Sangue Fetal/imunologia, Infecções por HIV/terapia, Infecções por HIV/epidemiologia, Infecções por HIV/imunologia, Infecções por HIV/virologia, Imunidade Materno-Adquirida, Imunoglobulina G/imunologia, Troca Materno-Fetal/imunologia, Placenta/metabolismo, Gravidez, Proteínas de Transporte, Fatores Sexuais, Vacinas/imunologia
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Placental Microparticles and MicroRNAs in Pregnant Women with Plasmodium falciparum or HIV Infection

Moro, Laura; Bardaji, Azucena; Macete, Eusebio; Barrios, Diana; Prieto, Diana M Morales; Espana, Carolina; Mandomando, Inacio; Sigauque, Betuel; Dobano, Carlota; Markert, Udo R; Ribas, Daniel Benitez; Alonso, Pedro L; Menendez, Clara; Mayor, Alfredo.
PLos ONE; 11 (1), 2016
During pregnancy, syncytiotrophoblast vesicles contribute to maternal tolerance towards the fetus, but also to pathologies such as pre-eclampsia. The aim of the study was to address whether Plasmodium falciparum and HIV infections in pregnancy affect the secretion, microRNA content and function of tropho...
Malária Falciparum/patologia, Malária Falciparum/metabolismo, Placenta/metabolismo, Resultado da Gravidez, Micropartículas Derivadas de Células/metabolismo, Micropartículas Derivadas de Células/ultraestrutura, Quimiocinas/metabolismo, Células Dendríticas/metabolismo, Demografia/estatística & dados numéricos, Recém-Nascido, MicroRNAs/metabolismo, Plasmodium falciparum/fisiologia, Trofoblastos/metabolismo, Moçambique
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