RDSM – Rede de Documentação sobre Saúde em Moçambique

Sustained clinical benefit of malaria chemoprevention with sulfadoxine-pyrimethamine (SP) in pregnant women in a region with high SP resistance markers

Matambisso, Glória; Brokhattingen, Nanna; Maculuve, Sónia; Cístero, Pau; Mbeve, Henriques; Escoda, Anna; Bambo, Gizela; Cuna, Boaventura; Melembe, Cardoso; Ndimande, Nelo; Tetteh, Kevin K. A; Drakeley, Chris; Gamain, Benoit; Chitnis, Chetan; Chauhan, Virander; Quintó, Llorenç; Macete, Eusébio; Mayor, Alfredo.

J. infect; 88 (5), 2024

Objective: The effectiveness of intermittent preventive treatment of malaria in pregnancy with sulfadoxine-pyrimethamine (IPTp-SP) is threatened by increasing SP-resistance in Africa. We assessed the level of SP-resistance markers, and the clinical and parasitological effectiveness of IPTp-SP in southern...

Pirimetamina, Malária Falciparum, Resistência a Medicamentos, Quimioprevenção/métodos, Antimaláricos/uso terapêutico, Sulfadoxina, Protocolos de Quimioterapia Combinada Antineoplásica, Complicações Parasitárias na Gravidez/terapia, Complicações Parasitárias na Gravidez/prevenção & controle, Moçambique/epidemiologia

Texto completo

Feasibility,acceptability, and protective efficacy of seasonal malaria chemoprevention implementation in nampula province, Mozambique: protocol for a hybrid effectiveness-implementation study

Seasonal malaria chemoprevention (SMC) is a highly effective community-based intervention to prevent malaria infections in areas where the malaria burden is high and transmission occurs mainly during the rainy season. In Africa, so far, SMC has been implemented in the Sahel region. Mozambique contributes...