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CD4(+)CD25(High) Treg cells in HIV/HTLV co-infected patients with neuropathy: high expression of Alpha4 integrin and lower expression of Foxp3 transcription factor

Chissumba, Raquel Matavele; Barbosa, Suse Dayse Silva; Augusto, Ângelo; Mumeia, Cremildo; Mabunda, Nédio; Jr, Eduardo Samo Gudo; Bhatt, Nilesh; Jani, Ilesh; Savino, Wilson.
BMC immunol. (Online); 52 (16), 2015
Regulatory CD4 T cells (Tregs) are critical in maintaining the homeostasis of the immune system. Quantitative or phenotypic alterations and functional impairment of Tregs have been associated with the development of pathologies including those of the central nervous system. Individuals with HIV-1/HTLV-1 ...
d0009060, Antígenos HLA-A/genética, Antígenos HLA-B/genética, d0017820, Antígenos HLA-DR/genética, Pacientes, d0024900, Teste de Histocompatibilidade, Coinfecção, HIV-1, Integrina alfa4, Infecções por HIV, Linfócitos T Reguladores, Sistema Imunitário, Vírus Linfotrópico T Tipo 1 Humano, Citometria de Fluxo
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Human leukocyte antigen–A, –B, and –DRB1 allele and haplotype frequencies in the Mozambican population: A blood donor–based population study

Assane, António A. A; Silva, Gustavo M. Fabricio; Oliveira, Juliana Cardoso; Mabunda, Nédio E. J; Sousa, Amina M; Jani, Ilesh V; Jr., Orlando C. Ferreira; Porto, Luis C. M. S.
Hum. immunol; 71 (10), 2010
Human leukocyte antigen (HLA) has been used for several decades as genetic markers for analyzing diversity of gene pool origin, platelet transfusion, tissue transplantation, disease susceptibility or resistance, and forensic and anthropological studies. In the present study, the allele and haplotype freq...
Antígenos HLA-A/genética, Antígenos HLA-B/genética, Antígenos HLA-DR/genética, Cadeias HLA-DRB1, Haplótipos, Teste de Histocompatibilidade, Moçambique
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