Transplacental transfer of antibodies is essential for conferring protection in newborns against infectious diseases. We assessed the impact of different factors, including gestational age and maternal infections such as HIV and malaria, on the efficiency of cord blood levels and placental transfer of Ig...
Background: A major unresolved safety concern for malaria case management is the use of artemisinin combination therapies (ACTs) in the first trimester of pregnancy. There is a need for human data to inform policy makers and treatment guidelines on the safety of artemisinin combination therapies (ACT) wh...
Background. Malaria and human immunodeficiency virus (HIV) during pregnancy affect the transplacental transfer of antibodies against several pathogens from mother to fetus, although their effect over antimalarial antibodies remains unclear.
Methods. Total immunoglobulin G (IgG), IgM and IgG subtypes aga...